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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESTMARQ/抗ZAK抗体(pThr161+pThr162)/SPC-1029D-A680/100-µl
商品详细STRESTMARQ/抗ZAK抗体(pThr161+pThr162)/SPC-1029D-A680/100-µl
STRESTMARQ/抗ZAK抗体(pThr161+pThr162)/SPC-1029D-A680/100-µl
STRESTMARQ/抗ZAK抗体(pThr161+pThr162)/SPC-1029D-A680/100-µl
商品编号: SPC-1029D-A680
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name ZAK Antibody (pThr161+pThr162)
Description

Rabbit Anti-Human ZAK (pThr161+pThr162) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr161 and Thr162 of human MLTK (AA158-165)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 91.181 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1029, RRID: AB_2708921
Certificate of Analysis A 1:250 dilution of SPC-1029 was sufficient for detection of ZAK (pThr161+pThr162) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names AZK antibody, Cervical cancer suppressor gene 4 protein antibody, HCCS 4 antibody, HCCS-4 antibody, Human cervical cancer suppressor gene 4 protein antibody, Leucine zipper and sterile alpha motif containing kinase antibody, Mitogen activated protein kinase kinase kinase MLT antibody, Mixed lineage kinase related kinase antibody, MLK 7 antibody, MLK related kinase antibody, MLK-like mitogen-activated protein triple kinase antibody, MLK-related kinase antibody, MLK7 antibody, Mlklak antibody, MLT antibody, MLTK_HUMAN antibody, ZAK antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_057737
Gene ID 51776
Swiss Prot Q9NYL2
Scientific Background Stress activated and proapoptotic member of the MAPKKK family. Regulates the JNK and p38 pathways. Involved in regulation of S and G2 cell cycle checkpoints by direct phosphorylation of CHEK2. MLTK causes cell shrinkage and disruption of actin stress fibers and phosphorylates histone H3 (Ser-28). It was suggested to play a role in cell transformation and oncogenesis.

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 ATTO 680
Overview:

  • High fluorescence yield
  • Excellent thermal and photostability
  • Quenched by electron donors
  • Very hydrophilic
  • Good solubility in polar solvents
  • Zwitterionic dye
  • Molar Mass: 631 g/mol

ATTO 680 Datasheet

 ATTO 680 Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 680 nm

λem = 700 nm

εmax = 1.25×105

Φf = 0.30

τfl = 1.7 ns

Brightness = 37.5

Laser = 633 – 676 nm

Filter set = Cy®5.5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。