STRESS MARQ/Y 27632/SIH-486-5MG/5-mg
商品编号：
SIH-486-5MG
市场价：
¥4700.00
美元价：
2820.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Y27632 |
| Description | ROCKkinaseinhibitor |
| Purity | >98%(HPLC) |
| CASNo. | 146986-50-7 |
| MolecularFormula | C14H23Cl2N3O |
| MolecularWeight | 320.3 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(25mg/ml),methanol(25mg/ml),acetonitrile(<1 mg/ml), dioxan (<1 mg/ml), water (very soluble |
| Source | Synthetic |
| Appearance | Whitetopaleyellowpowder |
| SMILES | C[[email protected]@H](N)[[email protected]]1CC[[email protected]@H](CC1)C(=O)NC2=CC=NC=C2.Cl.Cl |
| InChI | InChI=1S/C14H21N3O/c1-10(15)11-2-4-12(5-3-11)14(18)17-13-6-8-16-9-7-13/h6-12H,2-5,15H2,1H3,(H,16,17,18)/t10-,11?,12?/m1/s1 |
| InChIKey | IYOZTVGMEWJPKR-VOMCLLRMSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302Acutetoxicity,Inhalation(Category4),H332Acutetoxicity,Dermal(Category4),H312SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302+H312+H332Harmfulifswallowed,incontactwithskinorifinhaledPrecautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/protectiveclothing.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P322Specificmeasures(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P363Washcontaminatedclothingbeforereuse.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | Y27632(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-486) |
BIOLOGicalDescription
| AlternativeNames | Y-27632dihydrochloride,(R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide.2HCl |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 448042 |
| ScientificBackground | Y27632isaverypotentandselectiveROCK1andROCK2inhibitor.Y27632iscellpermeableandisanATPcompetitiveinhibitor. |
| References | 1.ShiJ.,etal.(2013)CellDeath&Disease,4:e483. |
ProductImages
ChemicalstructureofY27632(SIH-486),aROCKfamilykinaseinhibitor.CAS#:146986-50-7.MolecularFormula:C14H23Cl2N3O.MolecularWeight:320.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
