StressMarq/Xanthohumol/SIH-370-50MG/50-mg
商品编号:
SIH-370-50MG
市场价:
¥14120.00
美元价:
8472.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | Xanthohumol |
Description | Autophagyinhibitor |
Purity | >98%(TLC);NMR(Conforms) |
CASNo. | 6754-58-1 |
MolecularFormula | C21H22O5 |
MolecularWeight | 354.4 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | MaybedissolvedinDMSO(35mg/ml)orEthanol(35mg/ml) |
Source | Synthetic |
Appearance | Yellowsolid |
SMILES | CC(=CCC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)C |
InChI | InChI=1S/C21H22O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-9,11-12,22,24-25H,10H2,1-3H3/b11-7+ |
InChIKey | ORXQGKIUCDPEAJ-YRNVUSSQSA-N |
SafetyPhrases | Classification:ToxicSafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H317Maycauseanallergicskinreaction.H400Verytoxictoaquaticlife.PrecautionaryPhrases:P273Avoidreleasetotheenvironment.P280Wearprotectivegloves. |
CiteThisProduct | Xanthohumol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-370) |
BIOLOGicalDescription
AlternativeNames | (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
ResearchAreas | Cancer,Autophagy |
PubChemID | 639665 |
ScientificBackground | Xanthohumolisavalosin-containingprotein(VCP)inhibitorwhichbindstotheN-domainofVCP,suppressingfunctionandimpairingautophagosomematuration(1).Italsoinhibitsgrowthofawidevarietyofhumancancercelllinesbyinhibitingproliferationandinducingapoptosis(2). |
References | 1.SasazawaY.,etal.(2012)ACSChemBiol.7(5):892-900. 2.VeneR.,etal.(2012)Mol.Med.18:1292. |
ProductImages
ChemicalstructureofXanthohumol(SIH-370),aAutophagyinhibitor.CAS#:6754-58-1.MolecularFormula:C21H22O5.MolecularWeight:354.4g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。