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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Xanthohumol/SIH-370-50MG/50-mg
商品详细StressMarq/Xanthohumol/SIH-370-50MG/50-mg
StressMarq/Xanthohumol/SIH-370-50MG/50-mg
StressMarq/Xanthohumol/SIH-370-50MG/50-mg
商品编号: SIH-370-50MG
市场价: ¥14120.00
美元价: 8472.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameXanthohumol
Description

Autophagyinhibitor

Purity>98%(TLC);NMR(Conforms)
CASNo.6754-58-1
MolecularFormulaC21H22O5
MolecularWeight354.4

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilityMaybedissolvedinDMSO(35mg/ml)orEthanol(35mg/ml)
SourceSynthetic
AppearanceYellowsolid
SMILESCC(=CCC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)C
InChIInChI=1S/C21H22O5/c1-13(2)4-10-16-18(24)12-19(26-3)20(21(16)25)17(23)11-7-14-5-8-15(22)9-6-14/h4-9,11-12,22,24-25H,10H2,1-3H3/b11-7+
InChIKeyORXQGKIUCDPEAJ-YRNVUSSQSA-N
SafetyPhrasesClassification:ToxicSafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H317Maycauseanallergicskinreaction.H400Verytoxictoaquaticlife.PrecautionaryPhrases:P273Avoidreleasetotheenvironment.P280Wearprotectivegloves.
CiteThisProductXanthohumol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-370)

BIOLOGicalDescription

AlternativeNames(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(­3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-­2-propen-1-one
ResearchAreasCancer,Autophagy
PubChemID639665
ScientificBackgroundXanthohumolisavalosin-containingprotein(VCP)inhibitorwhichbindstotheN-domainofVCP,suppressingfunctionandimpairingautophagosomematuration(1).Italsoinhibitsgrowthofawidevarietyofhumancancercelllinesbyinhibitingproliferationandinducingapoptosis(2).
References1.SasazawaY.,etal.(2012)ACSChemBiol.7(5):892-900.
2.VeneR.,etal.(2012)Mol.Med.18:1292.

ProductImages

<p>Chemical structure of Xanthohumol (SIH-370), a Autophagy inhibitor. CAS #: 6754-58-1. Molecular Formula: C21H22O5. Molecular Weight: 354.4 g/mol.</p>

ChemicalstructureofXanthohumol(SIH-370),aAutophagyinhibitor.CAS#:6754-58-1.MolecularFormula:C21H22O5.MolecularWeight:354.4g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。