STRESS MARQ/VU0467154/SIH-184-10MG/10MG
商品编号：
SIH-184-10MG
市场价：
¥4100.00
美元价：
2460.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | VU0467154 |
| Description | M4ReceptorAgoNIST |
| Purity | 95.11% |
| CASNo. | 1451993-15-9 |
| MolecularFormula | C17H15F3N4O3S2 |
| MolecularWeight | 444.45 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | BlueIceor4ºC |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO |
| Source | Synthetic |
| Appearance | TanSolid |
| SMILES | O=S(C1=CC=C(C=C1)CNC(C2=C(N)C3=C(C)C(C)=NN=C3S2)=O)(C(F)(F)F)=O |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | VU0467154(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-184) |
BIOLOGicalDescription
| AlternativeNames | 5-amino-3,4-dimethyl-N-(4-((trifluoromethyl)sulfonyl)benzyl)thieno[2,3-c]pyridazine-6-carboxamide |
| ResearchAreas | Neurodegeneration,Neuroscience,NeurotransmitterReceptors,NMDAReceptors |
| PubChemID | PMC4324418 |
| ScientificBackground | AllostericactivatorsoftheM4muscarinicacetylcholinereceptorrepresentanovelapproachforthetreatmentofpsychoticsymptomsassociatedwithschizophreniaandotherneuropsychiatricdisorders.VU0467154producedarobustdose-dependentreversalofMK-801-inducedhyperlocomotionanddeficitsinpreclinicalmodelsofassociativelearningandmemoryfunctionsinwild-typemice,butfailedtoreversethesestimulant-induceddeficitsinM4KOmice.VU0467154alsoenhancedtheacquisitionofbothcontextualandcue-mediatedfearconditioningwhenadministeredaloneinwild-typemice. |
| References | 1.BubserM.,et.al.(2014)ACSClinicalNeuroscience5:920-942. |
ProductImages
ChemicalstructureofVU0467154(SIH-184),aM4ReceptorAgonist.CAS#:1451993-15-9.MolecularFormula:C17H15F3N4O3S2.MolecularWeight:444.45g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
