4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/抗VEGF受体1抗体/SPC-1210D-BI/100-µl
商品详细StressMarq/抗VEGF受体1抗体/SPC-1210D-BI/100-µl
StressMarq/抗VEGF受体1抗体/SPC-1210D-BI/100-µl
StressMarq/抗VEGF受体1抗体/SPC-1210D-BI/100-µl
商品编号: SPC-1210D-BI
市场价: ¥6760.00
美元价: 4056.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameVEGFReceptor1Antibody
Description

RabbitAnti-HumanVEGFReceptor1Polyclonal

SpeciesReactivityHuman,Mouse
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenSyntheticpeptideofhumanVEGFReceptor1(AA143-158)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects151kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1210,RRID:AB_2712161
CertificateofAnalysisA1:250dilutionofSPC-1210wassufficientfordetectionofVEGFReceptor1in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesEC2.7.10.1Antibody,FLT1Antibody,FLTAntibody,Flt-1Antibody,FLT1Antibody,Fmsliketyrosinekinase1Antibody,Fmsrelatedtyrosinekinase1Antibody,Fmsrelatedtyrosinekinase1(vascularendothelialgrowthfactor/vascularpermeABIlityfactorreceptor)Antibody,Fmsrelatedtyrosinekinase1vascularendothelialgrowthfactor/vascularpermeabilityfactorreceptorAntibody,Fms-liketyrosinekinase1Antibody,FRTAntibody,SolubleVEGFreceptor114Antibody,SolubleVEGFR1variant2Antibody,SolubleVEGFR1variant21Antibody,TyrosineproteinkinaseFRTAntibody,TyrosineproteinkinasereceptorFLTAntibody,Tyrosine-proteinkinaseFRTAntibody,Tyrosine-proteinkinasereceptorFLTAntibody,Vascularendothelialgrowthfactorreceptor1Antibody,VascularendothelialgrowthfactorvascularpermeabilityfactorreceptorAntibody,Vascularpermeabilityfactorreceptor1Antibody,VascularpermeabilityfactorreceptorAntibody,VEGFR1Antibody,VEGFR-1Antibody,VEGFR1Antibody,VGFR1_HUMANAntibody
CellularLocalizationCytoplasm,Cellmembrane,Secreted
AccessionNumberNP_002010
GeneID2321
SwissProtP17948
ScientificBackgroundFLT1isareceptor-tyrosinekinasethatisactivateduponbindingwithVEGF-A,VEGF-BandPGF.Itplaysanimportantroleinthedevelopmentofembryonicvasculature,andasanegativeregulatorofembryonicangiogenesisbyinhibitingexcessiveproliferationofendothelialcells.However,itcanpromotePGF-mediatedendothelialcellproliferation,survivalandangiogenesisinadults,althoughthisseemstobecell-typespecific.Italsocontributestocancercellsurvival,proliferation,migration,andinvasion,aswellastumourangiogenesis,metastasis,andrecruitmentoftumour-infiltratingmacrophages.IthasaveryhighaffinityforVEGF-AandmayfunctionasanegativeregulatorofVEGF-AsignallingbylimitingtheamountoffreeVEGF-AandpreventingitsbindingtoKDR.IsoformslackingatransmembranedomainmayfunctionasdecoyreceptorsforVEGF-A.FurThermore,itmediatesphosphorylationofPI3K,leADIngtoactivationofthedownstreamsignallingpathway,aswellasmediatingtheactivationoftheMAPKsignallingpathway,andoftheAkt/PKBsignallingpathway.

ProductImages

Currentlytherearenoimagesforthisproduct

ProductCitations(0)

Currentlytherearenocitationsforthisproduct.

BiotinBiotin Conjugate Structure

Properties:

  • BindstetramericavidinproteinsincludingStreptavidinandneuravidinwithveryhighaffinity
  • Molarmass:244.31g/mol
  • Formula:C10H16N2O3S
  • Applications:Westernblot,immunohistochemistry,andELISA

BiotinDatasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。