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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Vatalanib Dihydrochloride/SIH-484-50MG/50-mg
商品详细StressMarq/Vatalanib Dihydrochloride/SIH-484-50MG/50-mg
StressMarq/Vatalanib Dihydrochloride/SIH-484-50MG/50-mg
StressMarq/Vatalanib Dihydrochloride/SIH-484-50MG/50-mg
商品编号: SIH-484-50MG
市场价: ¥4500.00
美元价: 2700.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameVatalanibDihydrochloride
Description

VEGFRKinhibitor

Purity96%
CASNo.212141-51-0
MolecularFormulaC20H17Cl3N4
MolecularWeight419.7

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(30mg/ml),ethanol(10mg/ml)withwarming;verypoorlysolubleinwater;maximumsolubilityinplainwaterisestimatedtobeabout10-20µM;buffers,serum,orotheradditivesmayincreaseordecreasetheaqueoussolubility.Alsosolubleinmethanol,andwater(≥10mg/ml)
SourceSynthetic
AppearanceSolid
SMILESC1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl
InChIInChI=1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H
InChIKeyAZUQEHCMDUSRLH-UHFFFAOYSA-N
SafetyPhrasesClassification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductVatalanibDihydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-484)

BIOLOGicalDescription

AlternativeNamesN-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinaminedihydrochloride
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CardiovascularSystem,CellSignaling,GrowthFactorReceptorInhibitors
PubChemID22386467
ScientificBackgroundVatalanibDihydrochlorideisaninhibitorofFlk,c-KitandPDGFR-β.IthasbeenshowntoinhibitVEGFR-dependenttumorangiogenesisandEGFR-andRET-dependenttumorcellproliferationandsurvival.
References1.HerbstR.S.,HeymachJ.V.,O’ReillyM.S.,OnnA.,&RyanA.J.(2007)ExpertOpin.Invest.Drugs.16(2):239–249.

ProductImages

<p>Chemical structure of Vatalanib Dihydrochloride (SIH-484), a VEGFRK inhibitor. CAS #: 212141-51-0. Molecular Formula: C20H17Cl3N4. Molecular Weight: 419.7 g/mol.</p>

ChemicalstructureofVatalanibDihydrochloride(SIH-484),aVEGFRKinhibitor.CAS#:212141-51-0.MolecularFormula:C20H17Cl3N4.MolecularWeight:419.7g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。