StressMarq/Vatalanib Dihydrochloride/SIH-484-50MG/50-mg
商品编号:
SIH-484-50MG
市场价:
¥4500.00
美元价:
2700.00
产品分类:
电泳缓冲液
公司分类:
Electrophoretic_buffer
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | VatalanibDihydrochloride |
Description | VEGFRKinhibitor |
Purity | 96% |
CASNo. | 212141-51-0 |
MolecularFormula | C20H17Cl3N4 |
MolecularWeight | 419.7 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO(30mg/ml),ethanol(10mg/ml)withwarming;verypoorlysolubleinwater;maximumsolubilityinplainwaterisestimatedtobeabout10-20µM;buffers,serum,orotheradditivesmayincreaseordecreasetheaqueoussolubility.Alsosolubleinmethanol,andwater(≥10mg/ml) |
Source | Synthetic |
Appearance | Solid |
SMILES | C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl |
InChI | InChI=1S/C20H15ClN4.2ClH/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14;;/h1-12H,13H2,(H,23,25);2*1H |
InChIKey | AZUQEHCMDUSRLH-UHFFFAOYSA-N |
SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
CiteThisProduct | VatalanibDihydrochloride(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-484) |
BIOLOGicalDescription
AlternativeNames | N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinaminedihydrochloride |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CardiovascularSystem,CellSignaling,GrowthFactorReceptorInhibitors |
PubChemID | 22386467 |
ScientificBackground | VatalanibDihydrochlorideisaninhibitorofFlk,c-KitandPDGFR-β.IthasbeenshowntoinhibitVEGFR-dependenttumorangiogenesisandEGFR-andRET-dependenttumorcellproliferationandsurvival. |
References | 1.HerbstR.S.,HeymachJ.V.,O’ReillyM.S.,OnnA.,&RyanA.J.(2007)ExpertOpin.Invest.Drugs.16(2):239–249. |
ProductImages
ChemicalstructureofVatalanibDihydrochloride(SIH-484),aVEGFRKinhibitor.CAS#:212141-51-0.MolecularFormula:C20H17Cl3N4.MolecularWeight:419.7g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。