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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Anti-Twist Antibody/SPC-1336D-ALP/100-µl
商品详细StressMarq/Anti-Twist Antibody/SPC-1336D-ALP/100-µl
StressMarq/Anti-Twist Antibody/SPC-1336D-ALP/100-µl
StressMarq/Anti-Twist Antibody/SPC-1336D-ALP/100-µl
商品编号: SPC-1336D-ALP
市场价: ¥5920.00
美元价: 3552.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name Twist Antibody
Description

Rabbit Anti-Human Twist Polyclonal

Species Reactivity Human, Mouse, Rat
Applications WB, IHC
Antibody Dilution WB (1:2000), IHC (1:200); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Peptide sequence around aa.18~22(S-N-S-E-E) derived from Human Twist1
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects ~21kDa, endogenous levels of total Twist1 protein.
Cite This Product StressMarq Biosciences Cat# SPC-1336, RRID: AB_2713835
Certificate of Analysis A 1:1000 dilution of SPC-1336 was sufficient for detection of Twist in 10 µg of mouse muscle cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names ACS3 Antibody, bHLHa38 Antibody, SCS Antibody, TWIST Antibody, Twist basic helix loop helix transcription factor 1 Antibody, Twist homolog 1 Antibody, Twist related protein 1 Antibody, TWIST1 Antibody
Research Areas Cancer, Cardiovascular System, Cell Signaling, Epigenetics, Epigenetics and Nuclear Signaling, Heart, Neuroscience
Cellular Localization Nucleus
Accession Number NP_000465.1
Gene ID 7291
Swiss Prot Q15672
Scientific Background TWIST1 is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. It has been implicated in cell lineage determination and differentiation. The strongest expression of this mRNA is in placental tissue, in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
References 1. Reinhold M.I., Kapadia R.M., Liao Z., Naski M.S. (2006) J Biol Chem. 281(3): 1381-1388.

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AP (Alkaline Phosphatase)

Properties:

  • Broad enzymatic activity for phosphate esters of alcohols, amines, pyrophosphate, and phenols
  • Commonly used to dephosphorylate the 5’-termini of DNA and RNA to prevent self-ligation
  • Catalyzes the conversion of:
    • Chromogenic substrates (e.g. pNPP, naphthol AS-TR phosphate, BCIP) into coloured products
    • Fluorogenic substrates (e.g. 4-methylumbelliferyl phosphate) into fluorescent products
  • Molecular weight: 140 kDa
  • Applications: Western blot, immunohistochemistry, and ELISA

AP Datasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。