StressMarq/Tunicamycin/SIH-397-5MG/5-mg
商品编号：
SIH-397-5MG
市场价：
¥2240.00
美元价：
1344.00
产品分类：
电泳缓冲液
公司分类：
Electrophoretic_buffer
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Tunicamycin |
| Description | Autophagyinducer |
| Purity | >98%(HPLC)asamixtureoftunicamycinA,B,CandD |
| CASNo. | 11089-65-9 |
| MolecularFormula | C39H64N4O16 |
| MolecularWeight | 844.95 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | SolubleinDMSO(>10mg/ml)orethanol(5mg/ml;warm). |
| Source | IsolatedfromStreptomyceslysosuperficus |
| Appearance | Whitesolid. |
| SMILES | [[email protected]@H]2(O[[email protected]](O[[email protected]]1O[[email protected]@H]([[email protected]@H](O)[[email protected]](O)[[email protected]]1NC(=O)C)CO)[[email protected]](NC(=O)C=CCC(C)C)[[email protected]@H](O)[[email protected]]2O)CC(O)[[email protected]]4O[[email protected]@H |
| SafetyPhrases | Classification:D1A-VeryToxicMaterialCausingImmediateandSeriousToxicEffects,Highlytoxicbyingestion,D2A-VeryToxicMaterialCausingOtherToxicEffects,Teratogen-ReproductivehazardSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H300-Fatalifswallowed.Precautionarystatements:P264-Washhandsthoroughlyafterhandling.P301+P310-IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician. |
| CiteThisProduct | Tunicamycin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-397) |
BIOLOGicalDescription
| AlternativeNames | TunicamycinfromStreptomycessp. |
| ResearchAreas | Cancer,Autophagy |
| ScientificBackground | Asanucleosideantibiotic,TunicamycinblockstheformationofproteinN-glycosidiclinkagesbyinhibitingthetransferofN-acetylglucosamine1-phosphatetodolicholmonophosphate.Thiscausesaninductionofglucose-regulatedprotein78(GRP78)mRNAexpression,whichinturnincreasesERstressandsubsequentlyinducesautophagy. |
| References | 1.UnalE.S.,etal.(2008)BiochimBiophysActa.1778(6):1407-14. 2.DingW.X.,etal.(2007)JBiolChem.282(7):4702-10. 3.IshiiS.,etal.(1987)JNeuRochem.49(5):1606-12. 4.ZhangJ.,etal.(2013)JSurgRes.183(2):929-35. |
ProductImages
ChemicalstructureofTunicamycin(SIH-397),aAutophagyinducer.CAS#:11089-65-9.MolecularFormula:C39H64N4O16.MolecularWeight:844.95g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
