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当前位置: 首页 > 产品中心 > Electrophoretic_buffer > StressMarq/Anti-TTK Antibody (pSer677)/SPC-1091D-A488/100-µl
商品详细StressMarq/Anti-TTK Antibody (pSer677)/SPC-1091D-A488/100-µl
StressMarq/Anti-TTK Antibody (pSer677)/SPC-1091D-A488/100-µl
StressMarq/Anti-TTK Antibody (pSer677)/SPC-1091D-A488/100-µl
商品编号: SPC-1091D-A488
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 电泳缓冲液
公司分类: Electrophoretic_buffer
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameTTKAntibody(pSer677)
Description

RabbitAnti-HumanTTK(pSer677)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingSer677ofhumanTTK(AA674-680)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects97.072kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1091,RRID:AB_2710037
CertificateofAnalysisA1:250dilutionofSPC-1091wassufficientfordetectionofTTK(pSer677)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesDualspecificityproteinkinaseTTKAntibody,ECSTYkinaseAntibody,ESKAntibody,FLJ38280Antibody,hMPS1Antibody,MonopolarSpindle1Like1Antibody,MPH1Antibody,Mps1Antibody,MPS1L1Antibody,PhosphotyrosinePickedThreonineKinaseAntibody,Phosphotyrosinepickedthreonine-proteinkinaseAntibody,PYTAntibody,RP3-357D13.2Antibody,ttkAntibody,TTKProteinKinaseAntibody,TTK_HUMANAntibody,cancer/testisantigen96Antibody,CT96Antibody
CellularLocalizationCytoskeleton,Membrane,Spindle
AccessionNumberNP_003309
GeneID7272
SwissProtP33981
ScientificBackgroundTTKisadual-specificityproteinkinasewithactivitytowardserine,threonineandtyrosineresidues.TTKwasfoundtohavearoleincellcycleprogressionthroughregulatingcentrosomeduplicationduringS-phase.ThisfunctionwasCDK2-mediatedbydirectactivationofTTK.OverexpressionordysregulationofTTKactivtiymaypromotecancerthroughaberrantduplicationofcentrosomesandpromotiongofaneuploidy.MutationsinTTKarehighlycorrelatedinthedevelopmentofmicrosatellite-unstablecolorectalcancers.Thesemutationsweretypicallylossoffunctionframeshifttruncation,howeverthefunctionalrelevanceofthemutationwasstillnotdetermined.

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 ATTO488
Overview:
  • Highfluorescenceyield
  • HighphotostABIlity
  • Veryhydrophilic
  • Excellentsolubilityinwater
  • Verylittleaggregation
  • Newdyewithnetchargeof-1
  • MolarMass:804g/mol 

ATTO488Datasheet

  ATTO 488 Fluorophore Excitation and Emission SpectraOpticalProperties:

λex =501nm

λem=523nm

εmax=9.0×104

Φf= 0.80

τfl =4.1ns

Brightness= 72

Laser = 488 nm

Filterset = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。