StressMarq/Anti-Tyrosine Hydroxylase Antibody/SPC-1337D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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StressMarq/Anti-Tyrosine Hydroxylase Antibody/SPC-1337D-BI/100-µl

商品编号： SPC-1337D-BI

品牌： StressMarq Biosciences

市场价： ¥5960.00

美元价： 3576.00

产地：美国(厂家直采)

公司：

产品分类：电泳缓冲液

公司分类： Electrophoretic_buffer

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name Tyrosine Hydroxylase Antibody

Description

Rabbit Anti-Human Tyrosine Hydroxylase Polyclonal

Species Reactivity Human, Mouse, Rat

Applications WB, IHC, ICC/IF, ELISA

Antibody Dilution WB (1:1000), IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen Synthesized unphosphorylated peptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 19 (A-V-SP-E-Q).

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects ~60kDa, endogenous levels of total Tyrosine Hydroxylase protein.
Cite This Product	StressMarq Biosciences Cat# SPC-1337, RRID: AB_2713853
Certificate of Analysis	A 1:1000 dilution of SPC-1337 was sufficient for detection of Tyrosine Hydroxylase in 10 µg of 3T3 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	Dystonia 14 Antibody, DYT14 Antibody, DYT5b Antibody, Protein Pale Antibody, TYH Antibody, Tyrosine 3 hydroxylase Antibody, Tyrosine 3 monooxygenase Antibody, Tyrosine hydroxylase Antibody
Research Areas	Cancer, Neuroscience, Neurotransmitter Receptors
Accession Number	NP_000351.2
Gene ID	7054
Swiss Prot	P07101
Scientific Background	Tyrosine hydroxylase, also known as tyrosine 3-monooxygenase, is the enzyme that converts amino acid L-Tyrosine to L-3, 4-Dihydroxyphenylalanine (L-DOPA). L-DOPA is a precursor to dopamine, which is then converted to norepinephrine and epinephrine (adrenaline). Dopamine, norepinephrine and epinephrine are all important neurotransmitters. Alterations in the activity of tyrosine hydroxylase may be involved in a number of neurological diseases such as Parkinson's and schizophrenia. This enzyme is also required for embryonic development.
References	1. Kumer S.C. and Vrana K.E. (1996) J Neurochem. 67: 443-462. 2. Bodeau-Péan S., et al. (1999) J Biol Chem. 274: 3469-3475.

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337). Tissue: Brain Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337) at 1:1000. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337). Tissue: Brain Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337) at 1:1000. The image on the right is treated with the synthesized peptide.

<p>Western blot analysis of Mouse 3T3 cell lysates showing detection of ~60kDa Tyrosine Hydroxylase protein using Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337). Lane 1: Mouse 3T3 cells treated with Forskolin (40nM, 30min). Lane 2: Untreated. Primary Antibody: Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337) at 1:1000. Predicted/Observed Size: ~60kDa.</p>

Western blot analysis of Mouse 3T3 cell lysates showing detection of ~60kDa Tyrosine Hydroxylase protein using Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337). Lane 1: Mouse 3T3 cells treated with Forskolin (40nM, 30min). Lane 2: Untreated. Primary Antibody: Rabbit Anti-Tyrosine Hydroxylase Polyclonal Antibody (SPC-1337) at 1:1000. Predicted/Observed Size: ~60kDa.

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Biotin

Properties:

Binds tetrameric avidin proteins including Streptavidin and neuravidin with very high affinity
Molar mass: 244.31 g/mol
Formula: C₁₀H₁₆N₂O₃S
Applications: Western blot, immunohistochemistry, and ELISA

Biotin Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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