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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-TNF alpha Antibody/SPC-1315D-A390/100-µl
商品详细StressMarq/Anti-TNF alpha Antibody/SPC-1315D-A390/100-µl
StressMarq/Anti-TNF alpha Antibody/SPC-1315D-A390/100-µl
StressMarq/Anti-TNF alpha Antibody/SPC-1315D-A390/100-µl
商品编号： SPC-1315D-A390
市场价： ¥6060.00
美元价： 3636.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name TNF alpha Antibody
Description

Rabbit Anti-Human TNF alpha Polyclonal

Species Reactivity Human, Mouse, Rat
Applications IHC, ICC/IF, ELISA
Antibody Dilution IHC (1:100), ICC/IF (1:500), ELISA (1:10000); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen Synthesized peptide derived from internal of human TNFA.
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects endogenous levels of total TNFA protein.
Cite This Product StressMarq Biosciences Cat# SPC-1315, RRID: AB_2713457
Certificate of Analysis A 1:100 dilution of SPC-1315 was sufficient for detection of TNF alpha in human HepG2 cells using Goat Anti-Rabbit IgG as the secondary antibody.

Biological Description

Alternative Names APC1 Antibody, APC1 protein Antibody, Cachectin Antibody, DIF Antibody, Differentiation inducing factor Antibody, Macrophage cytotoxic factor Antibody, TNF alpha Antibody, Tnf Antibody, TNF superfamily, member 2 Antibody, TNF, macrophage derived Antibody, TNF, monocyte derived Antibody, TNF-a Antibody, TNF-alpha Antibody, TNFA Antibody, TNFA_HUMAN Antibody, TNFSF2 Antibody, Tumor necrosis factor alpha Antibody, Tumor necrosis factor Antibody, Tumor necrosis factor ligand superfamily member 2 Antibody, Tumor Necrosis Factor, Membrane Form Antibody, Tumor necrosis factor, soluble form Antibody
Cellular Localization Cell membrane
Accession Number NP_000585.2
Gene ID 7124
Swiss Prot P01375
Scientific Background Tumor necrosis factor is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. The primary role of TNF is in the regulation of immune cells. TNF, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1 & IL6 producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, Psoriasis and inflammatory bowel disease (IBD).
References 1. Swardfager W et al. (2010) Biol Psychiatry 68 (10): 930–941.
2. Locksley RM et al. (2001) Cell 104 (4): 487–501.
3. Dowlati Y et al. (2010) Biol Psychiatry 67 (5): 446–457.
4. Victor FC and Gottlieb AB (2002) J Drugs Dermatol 1 (3): 264–75.
5. Brynskov J. (2002) Gut 51 (1): 37–43.

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315). Tissue: Colon Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315). Tissue: Colon Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315). Tissue: HepG2 cells. Species: Human. Primary Antibody: Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunocytochemistry/Immunofluorescence analysis using Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315). Tissue: HepG2 cells. Species: Human. Primary Antibody: Rabbit Anti-TNF alpha Polyclonal Antibody (SPC-1315) at 1:100. The image on the right is treated with the synthesized peptide.

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  ATTO 390
Overview:

  • High fluorescence yield
  • Large Stokes-shift (89 nm)
  • Good photostability
  • Moderately hydrophilic
  • Good solubility in polar solvents
  • Coumarin derivate, uncharged
  • Low molar mass: 343.42 g/mol 

ATTO 390 Datasheet

ATTO 390 Fluorescent Dye Excitation and Emission SpectraOptical Properties:

λex = 390 nm

λem = 479 nm

εmax = 2.4×104

Φf = 0.90

τfl = 5.0 ns

Brightness = 21.6

Laser = 365 or 405 nm

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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