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当前位置： 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-TrpC4 Antibody [S77-15]/SMC-315D-HRP/100-µg
商品详细StressMarq/Anti-TrpC4 Antibody [S77-15]/SMC-315D-HRP/100-µg
StressMarq/Anti-TrpC4 Antibody [S77-15]/SMC-315D-HRP/100-µg
StressMarq/Anti-TrpC4 Antibody [S77-15]/SMC-315D-HRP/100-µg
商品编号： SMC-315D-HRP
市场价： ¥6580.00
美元价： 3948.00
产地： 美国(厂家直采)
公司：
产品分类： 酸碱缓冲液
公司分类： acid_base_buffer_solution
联系Q Q： 3392242852
电话号码： 4000-520-616
电子邮箱： info@ebiomall.com
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商品介绍

Overview:

Product Name TrpC4 Antibody
Description

Mouse Anti-Rat TrpC4 Monoclonal IgG1

Species Reactivity Human, Mouse, Rat
Applications WB, IHC, ICC/IF, IP, AM
Antibody Dilution WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
Host Species Mouse
Immunogen Species Rat
Immunogen Synthetic peptide amino acids 930-947 of rat TrpC4
Concentration 1 mg/ml
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.09% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Protein G Purified
Clonality Monoclonal
Clone Number S77-15
Isotype IgG1
Specificity Detects ~110kDa.
Cite This Product StressMarq Biosciences Cat# SMC-315, RRID: AB_2208049
Certificate of Analysis 1 µg/ml of SMC-315 was sufficient for detection of TrpC4 in 10 µg of COS cell lysate transiently transfected with TrpC4 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Biological Description

Alternative Names CCE1 Antibody, HTRP4 Antibody, STRPC4 Antibody, TRP4 Antibody, TRPC 4 Antibody, transient receptor potential 4 Antibody
Research Areas Cell Signaling, Ion Channels, Neuroscience, Transient Receptor Potential (TRP) Channels, Transient Receptor Potential Channels
Cellular Localization Cell membrane
Accession Number NP_001076584.1
Gene ID 84494
Swiss Prot O35119
Scientific Background Transient receptor potential cation channel, subfamily C, member 4, also known as TRPC4, is a human gene encoding a protein of the same name. They are expressed in smooth muscle and endothelial cells where they regulate membrane potential and calcium influx. TrpC4 is activated by G(q)/phospholipase C-coupled receptors, but the underlying mechanism remains elusive (1). Studies suggest TrpC4 contributes to axonal regeneration after nerve injury (2).
References 1. Otsuguro K., et al. (2008) J Biol Chem. 283(15): 10026-10036.
2. Wu D., Huang W., Richardson P.M., Pristly J.V., Liu M. (2008) J. Biol. Chem. 283(1): 416-426.

Product Images

<p>Immunohistochemistry analysis using Mouse Anti-TrpC4 Monoclonal Antibody, Clone S77-15 (SMC-315). Tissue: hippocampus. Species: Human. Fixation: Bouin’s Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-TrpC4 Monoclonal Antibody (SMC-315) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT.</p>

Immunohistochemistry analysis using Mouse Anti-TrpC4 Monoclonal Antibody, Clone S77-15 (SMC-315). Tissue: hippocampus. Species: Human. Fixation: Bouin’s Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-TrpC4 Monoclonal Antibody (SMC-315) at 1:1000 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT.

Product Citations (2)

Other Citations

Biomarker Analysis with Grating Coupled Surface Plasmon Coupled Fluorescence.

Mendoza, A., Dias, J.A., Zeltner, T. and Lawrence, D.A. (2014) J Adv Bio & Biotech. 1(1): 1-22.

PubMed ID: N/A Reactivity Human Applications: Antibody Microarray

Biomarker Analysis with Grating Coupled Surface Plasmon Coupled Fluorescence.

Mendoza, A., Dias, J.A., Zeltner, T. and Lawrence, D.A. (2014) J Adv Bio & Biotech. 1(1): 1-22.

PubMed ID: N/A Reactivity Mouse Applications: Antibody Microarray

HRP (Horseradish peroxidase)

Properties:

  • Enzymatic activity is used to amplify weak signals and increase visibility of a target
  • Readily combines with hydrogen peroxide (H2O2) to form HRP-H2O2 complex which can oxidize various hydrogen donors
  • Catalyzes the conversion of:
    • Chromogenic substrates (e.g. TMB, DAB, ABTS) into coloured products
    • Chemiluminescent substrates (e.g. luminol and isoluminol) into light emitting products via enhanced chemiluminescence (ECL)
    • Fluorogenic substrates (e.g. tyramine, homovanillic acid, and 4-hydroxyphenyl acetic acid) into fluorescent products
  • High turnover rate enables rapid generation of a strong signal
  • 44 kDa glycoprotein
  • Extinction coefficient: 100 (403 nm)
  • Applications: Western blot, immunohistochemistry, and ELISA

HRP Datasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
公司介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒
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CLIA套件 兴奋剂 敌手 抑制剂 蛋白质 活化剂 抗氧化剂 氧化还原探针 多克隆
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