StressMarq/Trichostatin A/SIH-254-5MG/5-mg
商品编号：
SIH-254-5MG
市场价：
¥9800.00
美元价：
5880.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | TrichostatinA |
| Description | HDACinhibitor |
| Purity | >98% |
| CASNo. | 58880-19-6 |
| MolecularFormula | C17H22N2O3 |
| MolecularWeight | 302.37 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto10mMinethanolandto50mMinDMSO |
| Source | Synthetic |
| Appearance | BeigeSolid |
| SMILES | C[[email protected]](/C=C(C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C |
| InChI | InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+ |
| InChIKey | RTKIYFITIVXBLE-WKWSCTOISA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R20/21/22-Harmfulbyinhilation,incontactwithskinandifswallowedR68-PossIBLeriskofirreversibleeffectsHazardPhrases:H302-H312-H315-H317-H319-H332-H335PrecautionaryPhrases:P261-P280-P305+P351+P338 |
| CiteThisProduct | TrichostatinA(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-254) |
BIOLOGicalDescription
| AlternativeNames | (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptADIenamide |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,HDACInhibitors |
| PubChemID | 444732 |
| ScientificBackground | TrichostatinAisanantifungalandselectivelyinhibitstheclassIandIImammalianhistondeacetlyasefamiliesofenzymes(1).TSAinhibitstheeukayoticcellcycleduringthebeginningofthegrowthstage.ItcanbeusedtoaltergeneexpressionbutinterferingwiththeremovalofacetylgroupstherebyalteringtheABIlityofDNAtranscriptionfactorstoaccesstheDNAinsidechromatin(2).Italsohasanti-cancerproperties(3). |
| References | 1.VanhaeckeT.,PapeleuP.,ElautG.,RogiersV.(2004)CurrMedChem.11(12):1629-1643. 2.Yoshida,etal.(1990)JBiolChem.165:17174. 3.DrummondD.C.,etal.(2005)AnnuRevPharmacolToxicol.45:495-528. |
ProductImages
ChemicalstructureofTrichostatinA(SIH-254),aHistonedeacetylaseinhibitor.CAS#:58880-19-6.MolecularFormula:C17H22N2O3.MolecularWeight:302.37g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
