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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-THRB Antibody/SPC-1314D-A700/100-µl
商品详细StressMarq/Anti-THRB Antibody/SPC-1314D-A700/100-µl
StressMarq/Anti-THRB Antibody/SPC-1314D-A700/100-µl
StressMarq/Anti-THRB Antibody/SPC-1314D-A700/100-µl
商品编号: SPC-1314D-A700
市场价: ¥6040.00
美元价: 3624.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameTHRBAntibody
Description

RabbitAnti-HumanTHRBPolyclonal

SpeciesReactivityHuman,Mouse,Rat
ApplicationsWB,IHC,ELISA
AntibodyDilutionWB(1:1000),IHC(1:100),ELISA(1:5000);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenSynthesizedpeptidederivedfromhumanThyroidHormoneReceptorβantibody.
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationAffinityPurified
ClonalityPolyclonal
IsotypeIgG
SpecificityDetects~42kDa,endogenouslevelsoftotalThyroidHormoneReceptorβprotein.
CiteThisProductStressMarqBiosciencesCat#SPC-1314,RRID:AB_2713439
CertificateofAnalysisA1:1000dilutionofSPC-1314wassufficientfordetectionofTHRBin10µgofLOVOcelllysatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesAvianerythroblasticleukemiaviral(verba)oncogenehomolog2Antibody,CERBA2Antibody,CERBABETAAntibody,c-erbA-2Antibody,c-erbA-betaAntibody,ERBA2Antibody,ERBABETAAntibody,ERBA2Antibody,Erythroblasticleukemiaviral(verba)oncogenehomolog2avianAntibody,generalizedresistancetothyroidhormoneAntibody,GRTHAntibody,MGC126109Antibody,MGC126110Antibody,NR1A2Antibody,Nuclearreceptorsubfamily1groupAmember2Antibody,OncogeneERBA2Antibody,PRTHAntibody,THB_HUMANAntibody,THR1Antibody,THRB1Antibody,THRB2Antibody,thrBAntibody,THRB1Antibody,THRB2Antibody,Thyroidhormonenuclearreceptorbetavariant1Antibody,Thyroidhormonereceptorbeta1Antibody,Thyroidhormonereceptorbeta2Antibody,ThyroidhormonereceptorbetaAntibody,Thyroidhormonereceptor,beta(erythroblasticleukemiaviral(verba)oncogenehomolog2,avian)Antibody
CellularLocalizationNucleus
AccessionNumberNP_000452.2
GeneID7068
SwissProtP10828
ScientificBackgroundTherearethreeformsofthethyroidhormonereceptordesignatedalpha-1,beta-1andbeta-2thatareabletobindthyroidhormone.TherearetwoTR-αreceptorsplicevariantsencodedbytheTHRAgeneandtwoTR-βisoformsplicevariantsencodedbytheTHRBgene.Thyroidhormonereceptorβ-1operatesasahormone-dependenttranscriptionalregulatorthatbindsDNAsequencesandisactivatedby3,5,3’-l-triiodothyronine(T3).Thyroidhormonereceptorβ-1isimportantinvertebratedevelopment,specificallyindevelopinglimbsandface.9-cis-retinoicacidreceptor(RXR)andretinoicacidreceptor(RAR)receptorfamiliesareoftenassociatedwiththyroidhormonereceptorβ-1andformhomodimersandheterodimers.
References1.FlamantFetal.(2006)PharmacolRev58(4):705–11.

ProductImages

<p>Immunohistochemistry analysis using Rabbit Anti-THRB Polyclonal Antibody (SPC-1314). Tissue: Lung Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-THRB Polyclonal Antibody (SPC-1314) at 1:100. The image on the right is treated with the synthesized peptide.</p>

ImmunohistochemistryanalysisusingRabbitAnti-THRBPolyclonalAntibody(SPC-1314).Tissue:LungCarcinomaTissue.Species:Human.Fixation:Formalinfixedparaffin-embedded.PrimaryAntibody:RabbitAnti-THRBPolyclonalAntibody(SPC-1314)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.

<p>Western blot analysis of Human LOVO cell lysates showing detection of ~42kDa THRB protein using Rabbit Anti-THRB Polyclonal Antibody (SPC-1314). Lane 1: Human LOVO cells. Lane 2: Human LOVO cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-THRB Polyclonal Antibody (SPC-1314) at 1:1000. Predicted/Observed Size: ~42kDa. Other Band(s): ~55kDa.</p>

WesternblotanalysisofHumanLOVOcelllysatesshowingdetectionof~42kDaTHRBproteinusingRabbitAnti-THRBPolyclonalAntibody(SPC-1314).Lane1:HumanLOVOcells.Lane2:HumanLOVOcellstreatedwiththeimmunizingpeptide.PrimaryAntibody:RabbitAnti-THRBPolyclonalAntibody(SPC-1314)at1:1000.Predicted/ObservedSize:~42kDa.OtherBand(s):~55kDa.

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 ATTO700
Overview:
  • Highfluorescenceyield
  • ExcellentthermalandphotostABIlity
  • Quenchedbyelectrondonors
  • Veryhydrophilic
  • Goodsolubilityinpolarsolvents
  • Zwitterionicdye
  • MolarMass:575g/mol

ATTO700Datasheet

 ATTO 700 Fluorophore Absorption and Emission SpectrumOpticalProperties:

λex =700 nm

λem=719nm

εmax=1.25×105

Φf= 0.25

τfl =1.6ns

Brightness= 31.3

Laser =676nm

Filterset =Cy®5.5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。