StressMarq/Thalidomide/SIH-336-500MG/500-mg
商品编号：
SIH-336-500MG
市场价：
¥5460.00
美元价：
3276.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Thalidomide |
| Description | E3UBligaseinhibitor |
| Purity | >98% |
| CASNo. | 50-35-1 |
| MolecularFormula | C13H10N2O4 |
| MolecularWeight | 258.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solublein5mg/mlDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O |
| InChI | InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17) |
| InChIKey | UEJJHQNACJXSKW-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Verytoxicmaterialcausingimmediateandserioustoxiceffects.Highlytoxicteratogen.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H302–HarmfulifswallowedH360–MaydamagefertilityortheunbornchildPrecautionaryStatements:P201–Obtainspecialinstructionsbeforeuse.P308+P313–Ifexposedorconcerned:Getmedicaladvice/attention. |
| CiteThisProduct | Thalidomide(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-336) |
BIOLOGicalDescription
| AlternativeNames | (±)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione,N-(2,6-dioxo-3-piperidinyl)phthalimide |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5426 |
| ScientificBackground | BindstotheE3ubiquitinligasecomplexformedbetweenCRBN,DDB1andCul4Ainhibitingligaseactivity.InhibitsTNFsynthesisandFGF-inducedangiogenesis.Cellpermeable.Caution:Teratogenic. |
| References | 1. ItoT.,etal.(2010)Science.327:1345. 2.WeglickiW.B.,etal.(1993)Mol.Cell.Biochem.129:195. 3.D’AmatoR.J.,etal.(1994)Proc.Natl.Acad.Sci.USA.91:4082. |
ProductImages
ChemicalstructureofThalidomide(SIH-336),aE3UBligaseinhibitor.CAS#:50-35-1.MolecularFormula:C13H10N2O4.MolecularWeight:258.2g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
