StressMarq/Anti-TGF beta 3 Antibody/SPC-1313D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-TGF beta 3 Antibody/SPC-1313D-BI/100-µl

StressMarq/Anti-TGF beta 3 Antibody/SPC-1313D-BI/100-µl

商品编号： SPC-1313D-BI

品牌： StressMarq Biosciences

市场价： ¥5960.00

美元价： 3576.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name TGF beta 3 Antibody

Description

Rabbit Anti-Human TGF beta 3 Polyclonal

Species Reactivity Human, Mouse, Rat

Applications WB, IHC, ELISA

Antibody Dilution WB (1:1000), IHC (1:100), ELISA (1:10000); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen Synthesized peptide derived from human TGF β3.

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects ~50kDa, endogenous levels of total TGF β3 protein.
Cite This Product	StressMarq Biosciences Cat# SPC-1313, RRID: AB_2713421
Certificate of Analysis	A 1:1000 dilution of SPC-1313 was sufficient for detection of TGF beta 3 in 10 µg of Cos7 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	ARVD Antibody, ARVD1 Antibody, FLJ16571 Antibody, MGC105479 Antibody, MGC118722 Antibody, prepro-transforming growth factor beta-3 Antibody, RNHF Antibody, TGF beta 3 Antibody, TGF beta3 Antibody, TGF-beta-3 Antibody, TGFB 3 Antibody, Tgfb3 Antibody, TGFB3_HUMAN Antibody, transforming growth factor beta 3 Antibody, Transforming growth factor beta-3 Antibody
Cellular Localization	Secreted
Accession Number	NP_003230.1
Gene ID	7043
Swiss Prot	P10600
Scientific Background	Transforming growth factor beta-3 is a protein that in humans is encoded by the TGFB3 gene. It is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG). TGF-β3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. Without TGF-β3, mammals develop a deformity known as a cleft palate. This is caused by failure of epithelial cells in both sides of the developing palate to fuse.
References	1. Bandyopadhyay B et al. (2006) The Journal of Cell Biology 172 (7): 1093–105. 2. Herpin A et al. (2004) Developmental and Comparative Immunology 28 (5): 461–85. 3. Taya Y et al. (1999) Development 126 (17): 3869–79. 4. Dudas M et al. (2004) Developmental Biology 266 (1): 96–108. 5. Kaartinen V et al. (1995) Nature Genetics 11 (4): 415–21.

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Western blot analysis of Monkey Cos7 cell lysates showing detection of ~12.5kDa TGF beta 3 protein using Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313). Lane 1: Monkey Cos7 cells. Lane 2: Monkey Cos7 treated with the immunizing peptide. Primary Antibody: Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313) at 1:1000. Predicted/Observed Size: ~12.5kDa .</p>

Western blot analysis of Monkey Cos7 cell lysates showing detection of ~12.5kDa TGF beta 3 protein using Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313). Lane 1: Monkey Cos7 cells. Lane 2: Monkey Cos7 treated with the immunizing peptide. Primary Antibody: Rabbit Anti-TGF beta 3 Polyclonal Antibody (SPC-1313) at 1:1000. Predicted/Observed Size: ~12.5kDa .

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Biotin

Properties:

Binds tetrameric avidin proteins including Streptavidin and neuravidin with very high affinity
Molar mass: 244.31 g/mol
Formula: C₁₀H₁₆N₂O₃S
Applications: Western blot, immunohistochemistry, and ELISA

Biotin Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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