StressMarq/Anti-TGF beta 1 Antibody/SPC-1312D-BI/100-µl-免疫在线蚂蚁淘旗下平台

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StressMarq/Anti-TGF beta 1 Antibody/SPC-1312D-BI/100-µl

商品编号： SPC-1312D-BI

品牌： StressMarq Biosciences

市场价： ¥5960.00

美元价： 3576.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name TGF beta 1 Antibody

Description

Rabbit Anti-Human TGF beta 1 Polyclonal

Species Reactivity Human, Mouse, Rat

Applications WB, IHC, ELISA

Antibody Dilution WB (1:1000), IHC (1:100), ELISA (1:5000); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen Synthesized peptide derived from human TGF β1 antibody.

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects ~45kDa, endogenous levels of total TGF β1 protein.
Cite This Product	StressMarq Biosciences Cat# SPC-1312, RRID: AB_2713403
Certificate of Analysis	A 1:1000 dilution of SPC-1312 was sufficient for detection of TGF beta 1 in 10 µg of HepG2 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	CED Antibody, DPD1 Antibody, LAP Antibody, Latency-associated peptide Antibody, Prepro transforming growth factor beta 1 Antibody, TGF beta 1 Antibody, TGF beta Antibody, TGF beta 1 protein Antibody, TGF-beta 1 protein Antibody, TGF-beta-1 Antibody, TGF-beta-5 Antibody, TGF-beta1 Antibody, TGFB Antibody, Tgfb-1 Antibody, tgfb1 Antibody, TGFB1_HUMAN Antibody, TGFbeta Antibody, TGFbeta1 Antibody, Transforming Growth Factor b1 Antibody, Transforming Growth Factor beta 1 Antibody, Transforming growth factor beta 1a Antibody, transforming growth factor beta-1 Antibody, transforming growth factor, beta 1 Antibody
Cellular Localization	Secreted
Accession Number	NP_000651.3
Gene ID	7040
Swiss Prot	P01137
Scientific Background	Transforming growth factor beta 1 or TGF-β1 is a polypeptide member of the transforming growth factor beta superfamily of cytokines. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
References	1. Ghadami M. et al. (2000) Am. J. Hum. Genet. 66 (1): 143–7. 2. Vaughn SP. et al. (2000) Genomics 66 (1): 119–21. 3. Assoian RK. et al. (1983) J. Biol. Chem. 258 (11): 7155–60. 4. Wahl SM et al. (1988) J. Immunol. 140 (9): 3026–32. 5. Tiemessen MM et al. (2003) Int. Immunol. 15 (12): 1495–504. 6. McGonigle S et al. (2001) FEBS Lett. 490 (1-2): 65–9.

Product Images

<p>Immunohistochemistry analysis using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:100. The image on the right is treated with the synthesized peptide.</p>

Immunohistochemistry analysis using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:100. The image on the right is treated with the synthesized peptide.

<p>Western blot analysis of Human HepG2 cell lysates showing detection of ~44kDa TGF beta 1 protein using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Lane 1: Human HepG2 cells. Lane 2: Human HepG2 cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:1000. Predicted/Observed Size: ~44kDa.</p>

Western blot analysis of Human HepG2 cell lysates showing detection of ~44kDa TGF beta 1 protein using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Lane 1: Human HepG2 cells. Lane 2: Human HepG2 cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:1000. Predicted/Observed Size: ~44kDa.

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Biotin

Properties:

Binds tetrameric avidin proteins including Streptavidin and neuravidin with very high affinity
Molar mass: 244.31 g/mol
Formula: C₁₀H₁₆N₂O₃S
Applications: Western blot, immunohistochemistry, and ELISA

Biotin Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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