StressMarq/Anti-TGF beta 1 Antibody/SPC-1312D-A488/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-TGF beta 1 Antibody/SPC-1312D-A488/100-µl

StressMarq/Anti-TGF beta 1 Antibody/SPC-1312D-A488/100-µl

商品编号： SPC-1312D-A488

品牌： StressMarq Biosciences

市场价： ¥6040.00

美元价： 3624.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName TGFbeta1Antibody

Description

RabbitAnti-HumanTGFbeta1Polyclonal

SpeciesReactivity Human,Mouse,Rat

Applications WB,IHC,ELISA

AntibodyDilution WB(1:1000),IHC(1:100),ELISA(1:5000);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Rabbit

ImmunogenSpecies Human

Immunogen SynthesizedpeptidederivedfromhumanTGFβ1antibody.

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	AffinityPurified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects~45kDa,endogenouslevelsoftotalTGFβ1protein.
CiteThisProduct	StressMarqBiosciencesCat#SPC-1312,RRID:AB_2713403
CertificateofAnalysis	A1:1000dilutionofSPC-1312wassufficientfordetectionofTGFbeta1in10µgofHepG2celllysatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	CEDAntibody,DPD1Antibody,LAPAntibody,Latency-associatedpeptideAntibody,Preprotransforminggrowthfactorbeta1Antibody,TGFbeta1Antibody,TGFbetaAntibody,TGFbeta1proteinAntibody,TGF-beta1proteinAntibody,TGF-beta-1Antibody,TGF-beta-5Antibody,TGF-beta1Antibody,TGFBAntibody,Tgfb-1Antibody,tgfb1Antibody,TGFB1_HUMANAntibody,TGFbetaAntibody,TGFbeta1Antibody,TransformingGrowthFactorb1Antibody,TransformingGrowthFactorbeta1Antibody,Transforminggrowthfactorbeta1aAntibody,transforminggrowthfactorbeta-1Antibody,transforminggrowthfactor,beta1Antibody
CellularLocalization	Secreted
AccessionNumber	NP_000651.3
GeneID	7040
SwissProt	P01137
ScientificBackground	Transforminggrowthfactorbeta1orTGF-β1isapolypeptidememberofthetransforminggrowthfactorbetasuperfamilyofcytokines.ManycellshaveTGFBreceptors,andtheproteinpositivelyandnegativelyregulatesmanyothergrowthfactors.Thesecretedproteiniscleavedintoalatency-associatedpeptide(LAP)andamatureTGFB1peptide,andisfoundineitheralatentformcomposedofaTGFB1homodimer,aLAPhomodimer,andalatentTGFB1-bindingprotein,orinanactiveformcomposedofaTGFB1homodimer.ThematurepeptidemayalsoformheterodimerswithotherTGFBfamilymembers.Thisgeneisfrequentlyupregulatedintumorcells,andmutationsinthisgeneresultinCamurati-Engelmanndisease.Itplaysanimportantroleinboneremodelingasitisapotentstimulatorofosteoblasticboneformation,causingchemotaxis,proliferationanddifferentiationincommittedosteoblasts.
References	1.GhadamiM.etal.(2000)Am.J.Hum.Genet.66(1):143–7. 2.VaughnSP.etal.(2000)Genomics66(1):119–21. 3.AssoianRK.etal.(1983)J.Biol.Chem.258(11):7155–60. 4.WahlSMetal.(1988)J.Immunol.140(9):3026–32. 5.TiemessenMMetal.(2003)Int.Immunol.15(12):1495–504. 6.McGonigleSetal.(2001)FEBSLett.490(1-2):65–9.

ProductImages

<p>Immunohistochemistry analysis using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Tissue: Breast Carcinoma Tissue. Species: Human. Fixation: Formalin fixed paraffin-embedded. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:100. The image on the right is treated with the synthesized peptide.</p>

ImmunohistochemistryanalysisusingRabbitAnti-TGFbeta1PolyclonalAntibody(SPC-1312).Tissue:BreastCarcinomaTissue.Species:Human.Fixation:Formalinfixedparaffin-embedded.PrimaryAntibody:RabbitAnti-TGFbeta1PolyclonalAntibody(SPC-1312)at1:100.Theimageontherightistreatedwiththesynthesizedpeptide.

<p>Western blot analysis of Human HepG2 cell lysates showing detection of ~44kDa TGF beta 1 protein using Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312). Lane 1: Human HepG2 cells. Lane 2: Human HepG2 cells treated with the immunizing peptide. Primary Antibody: Rabbit Anti-TGF beta 1 Polyclonal Antibody (SPC-1312) at 1:1000. Predicted/Observed Size: ~44kDa.</p>

WesternblotanalysisofHumanHepG2celllysatesshowingdetectionof~44kDaTGFbeta1proteinusingRabbitAnti-TGFbeta1PolyclonalAntibody(SPC-1312).Lane1:HumanHepG2cells.Lane2:HumanHepG2cellstreatedwiththeimmunizingpeptide.PrimaryAntibody:RabbitAnti-TGFbeta1PolyclonalAntibody(SPC-1312)at1:1000.Predicted/ObservedSize:~44kDa.

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ATTO488

Overview:

Highfluorescenceyield
HighphotostABIlity
Veryhydrophilic
Excellentsolubilityinwater
Verylittleaggregation
Newdyewithnetchargeof-1
MolarMass:804g/mol

ATTO488Datasheet

ATTO 488 Fluorophore Excitation and Emission Spectra

OpticalProperties:

λ_ex =501nm

λ_em=523nm

ε_max=9.0×10⁴

Φ_f= 0.80

τ_fl =4.1ns

Brightness= 72

Laser = 488 nm

Filterset = FITC

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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