StressMarq/Teprenone/SIH-526-50MG/50-mg
商品编号：
SIH-526-50MG
市场价：
¥3900.00
美元价：
2340.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Teprenone |
| Description | HSP70Inducer |
| Purity | >95%(GC) |
| CASNo. | 6809-52-5 |
| MolecularFormula | C23H38O |
| MolecularWeight | 330.6 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | SolubleinDMSO(30mg/ml) |
| Source | Synthetic |
| Appearance | ColorlessOil |
| SMILES | CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CCC(=O)C)/C)/C)/C)C |
| InChI | InChI=1S/C23H38O/c1-19(2)11-7-12-20(3)13-8-14-21(4)15-9-16-22(5)17-10-18-23(6)24/h11,13,15,17H,7-10,12,14,16,18H2,1-6H3/b20-13+,21-15+,22-17+ |
| InChIKey | HUCXKZBETONXFO-NJFMWZAGSA-N |
| SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | Teprenone(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-526) |
BIOLOGicalDescription
| AlternativeNames | Geranylgeranylacetone,GGA,6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one |
| ResearchAreas | Cancer,HeatShock,CellSignaling,Neuroscience |
| PubChemID | 5282199 |
| ScientificBackground | TeprenonecaninduceexpressionofHSP70,HSPB8,andHSPB1.InductionofHSP70expressionisprotectiveagainstthedevelopmentofvariousdiseases,suchasinflammatoryboweldisease,hypoxic/ischemicbraininjuryandspinalandbulbarmuscularatrophy(cytoprotectiveandanti-inflammatoryeffects)(1,2).ReportsindicatethatTeprenoneprotectsagainstNSAID-inducedgastricandintestinallesionsbyinductionofHSP70expression(2).OtherstudieshaveshownthatitinducesexpressionofHSPB8andHSPB1andreducestheformationofamyloidoligomersaswellasinsolubleaggregatesinHSPB5R120GTGmice(3,4). |
| References | 1.KobayashiT.,OhtaY.,YoshinoJandNakazawaS.(2001)PharmacolRes.43(1):23-30. 2.SambroskiP.,GrzymislawskiM.(2015)AdvClinMed.24(3):525-530. 3.MarunouchiT.,InomataS.,SanbeA.,TakagiN.,TanonakaK.(2014)EurJPharmacol.730:1401-47. 4.SanbeA.,etal.(2009)PLoSOne.4(4):e5351. |
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
