StressMarq/Temozolomide/SIH-363-100MG/100-mg
商品编号：
SIH-363-100MG
市场价：
¥4640.00
美元价：
2784.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Temozolomide |
| Description | AGTinhibitor |
| Purity | >99%(TLC);NMR(Conforms) |
| CASNo. | 85622-93-1 |
| MolecularFormula | C6H6N6O2 |
| MolecularWeight | 194.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(25mg/ml,warm)orwater(weakly) |
| Source | Synthetic |
| Appearance | Offwhitepowder |
| SMILES | CN1C(=O)N2C=NC(=C2N=N1)C(=O)N |
| InChI | InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13) |
| InChIKey | BPEGJWRSRHCHSN-UHFFFAOYSA-N |
| SafetyPhrases | Classification:ToxicSafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H302Harmfulifswallowed.H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.H350Maycausecancer.H360Maydamagefertilityortheunbornchild.PrecautionaryPhrases:P201Obtainspecialinstructionsbeforeuse.P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P308+P313IFexposedorconcerned:Getmedicaladviceorattention. |
| CiteThisProduct | Temozolomide(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-363) |
BIOLOGicalDescription
| AlternativeNames | 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide;8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 5394 |
| ScientificBackground | TemozolomideisamembranepermeableDNAalkylatingagentwhichactsasananti-tumorandanti-angiogenicagentbyalkylatingtheN-7orO-6positionsofguanineresidueswhichtriggerstumorcelldeath(1-2).Ithasbeenusedclinicallyasananti-canceragent(3)andhasbeenfoundtoinduceautophagyinavarietyofcelllines(4). |
| References | 1.KurzenH.,etal.(2003)AnticancerDrugs.14:515. 2.GuntherW.,etal.(2003)Br.J.Cancer.88:463. 3.DansonS.J.,etal.(2001)ExpertRev.AnticancerTher.10:13. 4.NatsumedaM.,etal.(2011)Neuropathology.31:486. |
ProductImages
ChemicalstructureofTemozolomide(SIH-363),aDNAalkylator/apoptosisinducer.CAS#:85622-93-1.MolecularFormula:C6H6N6O2.MolecularWeight:194.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
