StressMarq/Sunitinib malate/SIH-482-5MG/5-mg
商品编号：
SIH-482-5MG
市场价：
¥1800.00
美元价：
1080.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Sunitinibmalate |
| Description | VEGFR,PDGFRkinaseinhibitor |
| Purity | >99% |
| CASNo. | 557795-19-4 |
| MolecularFormula | C22H27FN4O2 |
| MolecularWeight | 398.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(40mg/ml) |
| Source | Synthetic |
| Appearance | Yellowsolid |
| SMILES | C1=CC2=C(C=C1F)C(/C(N2)=O)=C/C3=C(C(=C([NH]3)C)C(NCCN(CC)CC)=O)C |
| InChI | InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12- |
| InChIKey | WINHZLLDWRZWRT-ATVHPVEESA-N |
| SafetyPhrases | Classification:Reproductivetoxicity(Category1B),H360Specifictargetorgantoxicity-repeatedexposure,Oral(Category1),H372SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H360Maydamagefertilityortheunbornchild.H372Causesdamagetoorgansthroughprolongedorrepeatedexposureifswallowed.Precautionarystatements:P201Obtainspecialinstructionsbeforeuse.P202Donothandleuntilallsafetyprecautionshavebeenreadandunderstood.P260Donotbreathedust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P281Usepersonalprotectiveequipmentasrequired.P308+P313IFexposedorconcerned:Getmedicaladvice/attention.P405Storelockedup. |
| CiteThisProduct | Sunitinibmalate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-482) |
BIOLOGicalDescription
| AlternativeNames | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide(2S)-2-hydroxybutanedioicacid(1:1)salt,SU011248,SU11248,SU112248 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CardiovascularSystem,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 5329102 |
| ScientificBackground | Sunitinibmalateisareceptortyrosinekinaseinhibitor.IthasbeenshowntotargetVEGF-R1,VEGF-R2,VEGF-R3,PDGF-Rα,PDGF-Rβ,KIT,c-KIT,FLT3,CSF-1R,Flk-1,andRET. |
| References | 1.HerseyP.,etal.(2009)AnnalsofOncology:ESMO.20Suppl6:vi35–40. |
ProductImages
ChemicalstructureofSunitinibmalate(SIH-482),aVEGFR,PDGFRkinaseinhibitor.CAS#:557795-19-4.MolecularFormula:C22H27FN4O2.MolecularWeight:398.5g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
