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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Sulindac Sulfone/SIH-262-10MG/10-mg
商品详细StressMarq/Sulindac Sulfone/SIH-262-10MG/10-mg
StressMarq/Sulindac Sulfone/SIH-262-10MG/10-mg
StressMarq/Sulindac Sulfone/SIH-262-10MG/10-mg
商品编号: SIH-262-10MG
市场价: ¥2040.00
美元价: 1224.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSulindacSulfone
Description

Sulindacmetabolite

Purity>98%
CASNo.59864-04-9
MolecularFormulaC20H17FO4S
MolecularWeight372.41

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInducer
SolubilitySolubleto25mMinDMSO,3mMinethanol
SourceSynthetic
AppearanceYellowsolid
SMILESCC1=C(C2=C(/C1=CC3=CC=C(C=C3)S(=O)(=O)C)C=CC(=C2)F)CC(=O)O
InChIInChI=1S/C20H17FO4S/c1-12-17(9-13-3-6-15(7-4-13)26(2,24)25)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h4-10H,11H2,1-2H3,(H,22,23)/b17-9-
InChIKeyMVGSNCBCUWPVDA-MFOYZWKCSA-N
SafetyPhrasesClassification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection
CiteThisProductSulindacSulfone(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-262)

BIOLOGicalDescription

AlternativeNames{(1Z)-5-Fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3-yl}aceticacid
ResearchAreasCancer,Apoptosis
PubChemID5472495
ScientificBackgroundSulindacisanonsteroidalanti-inflammatorydrugthatisknowntopreventrecurrenceandreducecolorectalpolyps.Itisaprodrugthatismetabolizedtoasulfideandsulfonederivativeinvivo.Themechanismofactionofbothistheselectiveinductionofapoptosis.Theanti-inflammatorypropertiesofsulindacaremediatedbyCOXinhibition(1,2).
References1.FrahmS.,etal.(2004)CancerCellInt.4:4.
2.PiazzaG.A.,etal.(1997)CancerRes.57(12):2452-2459.

ProductImages

<p>Chemical structure of Sulindac Sulfone (SIH-262), a Modulates beta-catenin-mediated effects. CAS #: 59864-04-9. Molecular Formula: C20H17FO4S . Molecular Weight: 372.41 g/mol.</p>

ChemicalstructureofSulindacSulfone(SIH-262),aModulatesbeta-catenin-mediatedeffects.CAS#:59864-04-9.MolecularFormula:C20H17FO4S.MolecularWeight:372.41g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。