StressMarq/Sulindac Sulfide/SIH-261-50MG/50-mg
商品编号：
SIH-261-50MG
市场价：
¥6580.00
美元价：
3948.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | SulindacSulfide |
| Description | COXinhibitor |
| Purity | >98% |
| CASNo. | 32004-67-4 |
| MolecularFormula | C20H17FO2S |
| MolecularWeight | 340.41 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto25mMinDMSO,3mMinethanol |
| Source | Synthetic |
| Appearance | Yellowsolid |
| SMILES | CC1=C(C2=C(/C1=CC3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O |
| InChI | InChI=1S/C20H17FO2S/c1-12-17(9-13-3-6-15(24-2)7-4-13)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h4-10H,11H2,1-2H3,(H,22,23)/b17- |
| InChIKey | LFWHFZJPXXOYNR-RQZCQDPDSA-N |
| SafetyPhrases | Classification:Toxic.Maybeharmfulorfatalifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R20/21/22-Harmfulbyinhalation,incontactwithskinandifswallowedR62-PossIBLeriskofimpairedfertilityHazardPhrases:H302-H317-H334-H361PrecautionaryPhrases:P261-P280-P342+P311 |
| CiteThisProduct | SulindacSulfide(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-261) |
BIOLOGicalDescription
| AlternativeNames | {(1Z)-5-Fluoro-2-methyl-1-[4-(methylsulfanyl)benzylidene]-1H-inden-3-yl}aceticacid |
| ResearchAreas | Cancer,Apoptosis |
| PubChemID | 1548887 |
| ScientificBackground | Sulindacisanonsteroidalanti-inflammatorydrugthatisknowntopreventrecurrenceandreducecolorectalpolyps.Itisaprodrugthatismetabolizedtoasulfideandsulfonederivativeinvivo.Themechanismofactionofbothistheselectiveinductionofapoptosis.Theanti-inflammatorypropertiesofsulindacaremediatedbyCOXinhibition(1,2). |
| References | 1.FrahmS.,etal.(2004)CancerCellInt.4:4. 2.PiazzaG.A.,etal.(1997)CancerRes.57(12):2452-2459. |
ProductImages
ChemicalstructureofSulindacSulfide(SIH-261),aNFkBinhibitor.CAS#:32004-67-4.MolecularFormula:C20H17FO2S.MolecularWeight:340.41g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
