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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/SU 4312/SIH-481-25MG/25-mg
商品详细StressMarq/SU 4312/SIH-481-25MG/25-mg
StressMarq/SU 4312/SIH-481-25MG/25-mg
StressMarq/SU 4312/SIH-481-25MG/25-mg
商品编号: SIH-481-25MG
市场价: ¥5900.00
美元价: 3540.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSU4312
Description

VEGFR,PDGFRkinaseinhibitor

Purity>98%(HPLC)
CASNo.07-07-12
MolecularFormulaC17H16N2O
MolecularWeight264.3

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(25mg/ml)
SourceSynthetic
AppearanceOrangesolid
SMILESC1=CC=CC3=C1C(=C/C2=CC=C(N(C)C)C=C2)/C(=O)N3
InChIInChI=1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h4-11H,1-2H3,(H,18,20)/b15-11-
InChIKeyUAKWLVYMKBWHMX-PTNGSMBKSA-N
SafetyPhrasesClassification:Skinirritation(Category2),H315Eyeirritation(Category2A),H319Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/eyeprotection/faceprotection.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant.
CiteThisProductSU4312(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-481)

BIOLOGicalDescription

AlternativeNames3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CardiovascularSystem,CellSignaling,TyrosineKinaseInhibitors
PubChemID6450842
ScientificBackgroundSU4312isapotentandselectiveinhibitorofVEGFRandPDGFRtyrosinekinases,includingVEGFR-2(Flk-1,KDR).
References1.ZamanG.J.,etal.(1999)Biochem.Pharm.57(1):57–64.
2.ShimotakeJ.,DeruginN.,WendlandM.,VexlerZ.S.,&FerrieroD.M.(2010)Stroke.41(2):343–349.
3.SchultheissC.,etal.(2006)Angiogenesis.9(2):59–65.

ProductImages

<p>Chemical structure of SU 4312 (SIH-481), a VEGFR / PDGFR kinase inhibitor. CAS #: 5812-07-7. Molecular Formula: C17H16N2O. Molecular Weight: 264.3 g/mol.</p>

ChemicalstructureofSU4312(SIH-481),aVEGFR/PDGFRkinaseinhibitor.CAS#:5812-07-7.MolecularFormula:C17H16N2O.MolecularWeight:264.3g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。