StressMarq/SU 4312/SIH-481-5MG/5-mg
商品编号：
SIH-481-5MG
市场价：
¥1500.00
美元价：
900.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | SU 4312 |
| Description | VEGFR, PDGFR kinase inhibitor |
| Purity | >98% (HPLC) |
| CAS No. | 07-07-12 |
| Molecular Formula | C17H16N2O |
| Molecular Weight | 264.3 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (25 mg/ml) |
| Source | Synthetic |
| Appearance | Orange solid |
| SMILES | C1=CC=CC3=C1C(=C/C2=CC=C(N(C)C)C=C2)/C(=O)N3 |
| InChI | InChI=1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h4-11H,1-2H3,(H,18,20)/b15-11- |
| InChIKey | UAKWLVYMKBWHMX-PTNGSMBKSA-N |
| Safety Phrases | Classification: Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity -single exposure (Category 3), Respiratory system, H335Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.Hazard statements: H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation.Precautionary statements: P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264 Wash skin thoroughly after handling. P271 Use only outdoors or in a well-ventilated area. P280 Wear protective gloves/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of soap and water. P304 + P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 Call a POISON CENTER or doctor/ physician if you feel unwell. P321 Specific treatment (see supplemental first aid instructions on this label). P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 Take off contaminated clothing and wash before reuse. P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. P501 Dispose of contents/ container to an approved waste disposal plant. |
| Cite This Product | SU 4312 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-481) |
Biological Description
| Alternative Names | 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one |
| Research Areas | Cancer, Apoptosis, Cancer Growth Inhibitors, Cardiovascular System, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 6450842 |
| Scientific Background | SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases, including VEGFR-2 (Flk-1, KDR). |
| References |
1. Zaman G.J., et al. (1999) Biochem. Pharm. 57(1): 57–64. 2. Shimotake J., Derugin N., Wendland M., Vexler Z.S., & Ferriero D.M. (2010) Stroke. 41(2): 343–349. 3. Schultheiss C., et al. (2006) Angiogenesis. 9(2): 59–65. |
Product Images
Chemical structure of SU 4312 (SIH-481), a VEGFR / PDGFR kinase inhibitor. CAS #: 5812-07-7. Molecular Formula: C17H16N2O. Molecular Weight: 264.3 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
