StressMarq/STO 609/SIH-479-5MG/5-mg
商品编号:
SIH-479-5MG
市场价:
¥1540.00
美元价:
924.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | STO609 |
Description | CAMKKkinaseinhibitor |
Purity | >98%(TLC) |
CASNo. | 52029-86-4 |
MolecularFormula | C21H14N2O5 |
MolecularWeight | 374.3 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO(10mg/ml) |
Source | Synthetic |
Appearance | Yellowsolid |
SMILES | CC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O |
InChI | InChI=1S/C19H10N2O3.C2H4O2/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18;1-2(3)4/h1-9H,(H,23,24);1H3,(H,3,4) |
InChIKey | WNRSTFUVBWNELX-UHFFFAOYSA-N |
SafetyPhrases | Classification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
CiteThisProduct | STO609(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-479) |
BIOLOGicalDescription
AlternativeNames | 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylicacid,acetatesalt |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 16760660 |
ScientificBackground | STO609isapotent,competitiveandselectiveinhibitorofCa2+/Calmodulin-dependentproteinkinasekinase(CaM-KK).STO609hasbeenshowntobindtotheCaMKKcatalyticdomain,consequentlyinhibitingautophosphorylation.ItisavaluabletoolforexploringtheroleoftheCaM-KKpathwayinvariousphysiologicalprocesses.STO609iscell-permeable. |
References | 1.Tokumitsu,H.,etal.(2002)J.Biol.Chem.277(18):15813–15818. 2.LevineY.C.,LiG.K.,&MichelT.(2007)J.Biol.Chem.282(28):20351–20364. 3.AndersonK.A.,etal.(2008)CellMetabolism.7(5):377–388. |
ProductImages
ChemicalstructureofSTO609(SIH-479),aCAMKKkinaseinhibitor.CAS#:52029-86-4.MolecularFormula:C21H14N2O5.MolecularWeight:374.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。