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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/STO 609/SIH-479-5MG/5-mg
商品详细StressMarq/STO 609/SIH-479-5MG/5-mg
StressMarq/STO 609/SIH-479-5MG/5-mg
StressMarq/STO 609/SIH-479-5MG/5-mg
商品编号: SIH-479-5MG
市场价: ¥1540.00
美元价: 924.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSTO609
Description

CAMKKkinaseinhibitor

Purity>98%(TLC)
CASNo.52029-86-4
MolecularFormulaC21H14N2O5
MolecularWeight374.3

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(10mg/ml)
SourceSynthetic
AppearanceYellowsolid
SMILESCC(=O)O.C1=CC=C2C(=C1)N=C3N2C(=O)C4=CC=CC5=C(C=CC3=C54)C(=O)O
InChIInChI=1S/C19H10N2O3.C2H4O2/c22-18-13-5-3-4-10-11(19(23)24)8-9-12(16(10)13)17-20-14-6-1-2-7-15(14)21(17)18;1-2(3)4/h1-9H,(H,23,24);1H3,(H,3,4)
InChIKeyWNRSTFUVBWNELX-UHFFFAOYSA-N
SafetyPhrasesClassification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductSTO609(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-479)

BIOLOGicalDescription

AlternativeNames7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylicacid,acetatesalt
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID16760660
ScientificBackgroundSTO609isapotent,competitiveandselectiveinhibitorofCa2+/Calmodulin-dependentproteinkinasekinase(CaM-KK).STO609hasbeenshowntobindtotheCaMKKcatalyticdomain,consequentlyinhibitingautophosphorylation.ItisavaluabletoolforexploringtheroleoftheCaM-KKpathwayinvariousphysiologicalprocesses.STO609iscell-permeable.
References1.Tokumitsu,H.,etal.(2002)J.Biol.Chem.277(18):15813–15818.
2.LevineY.C.,LiG.K.,&MichelT.(2007)J.Biol.Chem.282(28):20351–20364.
3.AndersonK.A.,etal.(2008)CellMetabolism.7(5):377–388.

ProductImages

<p>Chemical structure of STO 609 (SIH-479), a CAMKK kinase inhibitor. CAS #: 52029-86-4. Molecular Formula: C21H14N2O5. Molecular Weight: 374.3 g/mol.</p>

ChemicalstructureofSTO609(SIH-479),aCAMKKkinaseinhibitor.CAS#:52029-86-4.MolecularFormula:C21H14N2O5.MolecularWeight:374.3g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。