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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-STI1P (HOP) Antibody/SPC-203D-A700/100-µl
商品详细StressMarq/Anti-STI1P (HOP) Antibody/SPC-203D-A700/100-µl
StressMarq/Anti-STI1P (HOP) Antibody/SPC-203D-A700/100-µl
StressMarq/Anti-STI1P (HOP) Antibody/SPC-203D-A700/100-µl
商品编号: SPC-203D-A700
市场价: ¥6400.00
美元价: 3840.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name STI1P (HOP) Antibody
Description

Rabbit Anti-Yeast STI1P (HOP) Polyclonal

Species Reactivity Mouse, Yeast
Applications WB, ELISA, FCM
Antibody Dilution WB (1:2500); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Yeast
Immunogen Yeast Sti1p raised against peptide(CDINQSNSMPKEPET)-KLH fusion
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer Rabbit Antiserum, PBS, 50% glycerol
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Rabbit antiserum
Clonality Polyclonal
Specificity Detects ~ 66kDa.
Cite This Product StressMarq Biosciences Cat# SPC-203, RRID: AB_2704163
Certificate of Analysis 0.5 µg/ml of SPC-203 was sufficient for detection of Sti1p (HOP) in 20 µg of W303 yeast lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names STIP1 Antibody, Sti1 yeast Antibody, Hop Antibody, HSC70/HSP90 organizing protein Antibody, Epididymis secretory sperm binding protein Li 94n antibody, HEL S 94n antibody, Hop antibody, HSC70/HSP90 organizing protein antibody, HSC70/HSP90-organizing protein antibody, IEF SSP 3521 antibody, NY REN 11 antigen antibody, P60 antibody, Renal carcinoma antigen NY-REN-11 antibody, STI1 antibody, STI1L antibody, STIP1 antibody, Stress induced phosphoprotein 1 antibody, Stress-induced-phosphoprotein 1 antibody, Transformation sensitive protein IEF SSP 3521 antibody, Transformation-sensitive protein IEF SSP 3521 antibody
Research Areas Cancer, Heat Shock
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_014670.1
Gene ID 854192
Swiss Prot P15705
Scientific Background The stress inducible protein Sti1p is also commonly known as HSP70-HSP90 organization protein (HOP). It is located in diverse cellular regions and can move between the cytoplasm and the nucleus. It functions to reversibly link together the protein chaperones HSP70 and HSP90. HOP contains three tetratricopeptide repeat (TPR) domains, TPR1, TPR2a and TPR2b. HSP70 binding has been localized to TRP1 and sp90 binding have been localized to TPR2a (1). It has also been found to modulate the chaperone activities of the linked proteins and possible interacts with other chaperones and proteins. It has also been found to participate in other complexes besides the HSP70/HSP90 one (2). HOP is closely related to human 63kDa protein that is sensitive to simian virus SV40 transformation, and is related to the yeast heat-shock- responsive STI1 gene product (3, 4).
References 1. Flom G., Behal R.H., Rosen L., Cole D.G., Johnson J.L. (2007) Biochem J. 404(1): 159-167.
2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt3): 789-796.
3. Honore B.H., et al. (1992) J Biol Chem. 267: 8485- 8491.
4. Nicolet C.M., et al. (1989) Mol Cell Bio. 9: 3638-3646.

Product Images

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Product Citations (2)

Flow Cytometry

Stress-Inducible Protein 1 (STI1): Extracellular Vesicle Analysis and Quantification.

Dias, M.V., Martins, V.R. and Hajj, G.N. (2016) Methods Mol Biol. 1459:161-74.

PubMed ID: 27665558 Reactivity Mouse Applications: Flow Cytometry

ELISA

Stress-Inducible Protein 1 (STI1): Extracellular Vesicle Analysis and Quantification.

Dias, M.V., Martins, V.R. and Hajj, G.N. (2016) Methods Mol Biol. 1459:161-74.

PubMed ID: 27665558 Reactivity Mouse Applications: ELISA

 ATTO 700
Overview:

  • High fluorescence yield
  • Excellent thermal and photostability
  • Quenched by electron donors
  • Very hydrophilic
  • Good solubility in polar solvents
  • Zwitterionic dye
  • Molar Mass: 575 g/mol

ATTO 700 Datasheet

 ATTO 700 Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 700 nm

λem = 719 nm

εmax = 1.25×105

Φf = 0.25

τfl = 1.6 ns

Brightness = 31.3

Laser = 676 nm

Filter set = Cy®5.5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。