StressMarq/Src I1/SIH-478-5MG/5-mg
商品编号：
SIH-478-5MG
市场价：
¥1200.00
美元价：
720.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | SrcI1 |
| Description | Srckinaseinhibitor |
| Purity | >98%(TLC) |
| CASNo. | 179248-59-0 |
| MolecularFormula | C22H19N3O3 |
| MolecularWeight | 373.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(5mg/ml) |
| Source | Synthetic |
| Appearance | Off-whitesolid |
| SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC |
| InChI | InChI=1S/C22H19N3O3/c1-26-20-12-18-19(13-21(20)27-2)23-14-24-22(18)25-15-8-10-17(11-9-15)28-16-6-4-3-5-7-16/h4-14H,1-2H3,(H,23,24,25) |
| InChIKey | DMWVGXGXHPOEPT-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Acutetoxicity,Oral(Category4),H302Skinirritation(Category2),H315Eyeirritation(Category2A),H319Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335Chronicaquatictoxicity(Category4),H413SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302Harmfulifswallowed.H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.H413Maycauselonglastingharmfuleffectstoaquaticlife.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/sprayP264Washskinthoroughlyafterhandling.P270Donoteat,drinkorsmokewhenusingthisproduct.P271Useonlyoutdoorsorinawell-ventilatedarea.P273Avoidreleasetotheenvironment.P280Wearprotectivegloves/eyeprotection/faceprotection.P301+P312IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P330Rinsemouth.P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant |
| CiteThisProduct | SrcI1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-478) |
BIOLOGicalDescription
| AlternativeNames | 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine,SKI-1,SrcInhibitor-1 |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 1474853 |
| ScientificBackground | SrcI1isapotentandcompetitivedualsiteSrckinaseinhibitor.IthasbeenshownasapotentinhibitoroftheSrcandLckkinase,aswellas,VEGFR2andc-fms.SrcI1iscellpermeableandcaninduceapoptosis. |
| References | 1.Bain,J.,etal.(2007)Biochem.J.408(3):297–315. 2.Leung,E.L.H.,etal.(2009)Mol.Cancer.Res:MCR.7(6):923–932. |
ProductImages
ChemicalstructureofSrcI1(SIH-478),aSrckinaseinhibitor.CAS#:179248-59-0.MolecularFormula:C22H19N3O3.MolecularWeight:373.4g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
