StressMarq/Spautin-1/SIH-404-5MG/5-mg
商品编号：
SIH-404-5MG
市场价：
¥1640.00
美元价：
984.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Spautin-1 |
| Description | Autophagyinhibitor |
| Purity | >98% |
| CASNo. | 1262888-28-7 |
| MolecularFormula | C15H11F2N3 |
| MolecularWeight | 271.26 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(15mg/ml). |
| Source | Synthetic |
| Appearance | Whitetobeigepowder. |
| SMILES | c1cc(ccc1CNc2c3cc(ccc3ncn2)F)F |
| InChI | InChI=1S/C15H11F2N3/c16-11-3-1-10(2-4-11)8-18-15-13-7-12(17)5-6-14(13)19-9-20-15/h1-7,9H,8H2,(H,18,19,20) |
| InChIKey | AWIVHRPYFSSVOG-UHFFFAOYSA-N |
| SafetyPhrases | Classification:D2B-ToxicMaterialCausingOtherToxicEffects,SevereeyeirritantSafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H302-Harmfulifswallowed.H318-Causesseriouseyedamage.Precautionarystatements:P280-Wearprotectivegloves/eyeprotection/faceprotection.P305+P351+P338-IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing. |
| CiteThisProduct | Spautin-1(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-404) |
BIOLOGicalDescription
| AlternativeNames | 6-Fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine |
| ResearchAreas | Cancer,Autophagy |
| PubChemID | 51037431 |
| ScientificBackground | Spautin-1inhibitsthedeubiquitinationactivityofUSP10andUSP13,twoubiquitin-specificpeptidases.ThisresultsinthedegradationofclassIIIPI3kinasecomplexes.Becausethisgroupofkinasesregulatesautophagy,Spautin-1inturninhibitsautophagy. |
| References | 1.LiuJ.,etal.(2011)Cell.147(1):223-34. |
ProductImages
ChemicalstructureofSpautin-1(SIH-404),aAutophagyinhibitor.CAS#:1262888-28-7.MolecularFormula:C15H11F2N3.MolecularWeight:271.26g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
