StressMarq/SP600125/SIH-381-50MG/50-mg
商品编号：
SIH-381-50MG
市场价：
¥5540.00
美元价：
3324.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | SP600125 |
| Description | Jnkinhibitor |
| Purity | >98% |
| CASNo. | 129-56-6 |
| MolecularFormula | C14H8N2O |
| MolecularWeight | 220.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSOormethanol |
| Source | Synthetic |
| Appearance | Yellowtobrownsolid |
| SMILES | C1=CC=C4C3=C1C(=O)C2=CC=CC=C2C3=N[NH]4 |
| InChI | InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16) |
| InChIKey | ACPOUJIDANTYHO-UHFFFAOYSA-N |
| SafetyPhrases | Classification:D2B-ToxicMaterialCausingOtherToxicEffects,Moderateskinirritant,Moderaterespiratoryirritant,ModerateeyeirritantSafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H315-Causesskinirritation.H319-Causesseriouseyeirritation.H335-MaycauserespiratoryirritationPrecautionaryPhrases:P261-Avoidbreathingdust/fume/gas/mist/vapours/spray.P264-Washskinthoroughlyafterhandling.P271-Useonlyoutdoorsorinawell-ventilatedarea.P280-Wearprotectivegloves/eyeprotection/faceprotection.P302+P352-IFONSKIN:Washwithplentyofsoapandwater.P304+P340-IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338-IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312–CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321-Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P332+P313-Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313-Ifeyeirritationpersists:Getmedicaladvice/attention.P362-Takeoffcontaminatedclothingandwashbeforereuse.P403+P233-Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405-Storelockedup.P501-Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | SP600125(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-381) |
BIOLOGicalDescription
| AlternativeNames | Anthra(1,9-cd)pyrazol-6(2H)-one,1,9-Pyrazoloanthrone |
| ResearchAreas | Cancer,Apoptosis,CellSignaling |
| PubChemID | 8515 |
| ScientificBackground | Selectiveinhibitorofc-JunN-terminalkinase(JNK).CompetitivelyandreversiblyinhibitsJNK1,2and3(IC50=40-90nM)withnegligibleactivityatERK2,p38βandarangeofenzymes(IC50>10µM).Activeinvivo.Showntohavereducedselectivityoverotherproteinkinasesundercertainconditions.Protectsrenaltubularepithelialcellsagainstischemia/reperfusion-inducedapoptosis. |
| References | 1.BennettB.L.,etal.(2001)Proc.Natl.Acad.Sci.U.S.A.98(24):13681-6. 2.SchnablB.,etal.(2001)Hepatology.34(5):953-63. 3.BainJ.,etal.(2003)Biochem.J.371(Pt1):199-204. 4.WangY.,etal.(2007)LifeSci.80(22):2067-75. |
ProductImages
ChemicalstructureofSP600125(SIH-381),aJnkinhibitor.CAS#:129-56-6.MolecularFormula:C14H8N2O.MolecularWeight:220.2g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
