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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-SOX2 Antibody/SPC-1287D-FITC/100-µl
商品详细StressMarq/Anti-SOX2 Antibody/SPC-1287D-FITC/100-µl
StressMarq/Anti-SOX2 Antibody/SPC-1287D-FITC/100-µl
StressMarq/Anti-SOX2 Antibody/SPC-1287D-FITC/100-µl
商品编号: SPC-1287D-FITC
市场价: ¥5880.00
美元价: 3528.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name SOX2 Antibody
Description

Rabbit Anti-Human SOX2 Polyclonal

Species Reactivity Human, Mouse, Rat
Applications WB, IHC, ICC/IF
Antibody Dilution WB (1:2000), IHC (1:200), ICC/IF (1:500); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A synthesized peptide derived from human SOX2
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Affinity Purified
Clonality Polyclonal
Isotype IgG
Specificity Detects ~34kDa, endogenous levels of total SOX2
Cite This Product StressMarq Biosciences Cat# SPC-1287, RRID: AB_2712971
Certificate of Analysis A 1:1000 dilution of SPC-1287 was sufficient for detection of SOX2 in 10 µg of HT29 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names SOX 2 Antibody, SRY (sex determining region Y) box 2 Antibody, SRY related HMG box 2 Antibody, SRY-box 2 Antibody, ANOP3 Antibody, ysb Antibody
Research Areas Embryonic Stem Cells, ESC Intracellular Markers, Germline Stem Cells, Stem Cells
Cellular Localization Nucleus
Accession Number NP_003097.1
Gene ID 6657
Swiss Prot P48431
Scientific Background The SOX (SRY-box containing gene) gene family encodes a group of transcription factors defined by the conserved high motility group (HMG) DNA-binding domain. They are involved in the regulation of embryonic development when it forms complexes with Oct4 and Nanog. Varying levels of Sox2 can affect the determination of cell fate. Sox2 inhibits differentiation into the mesendoderm germ layer and promotes differentiation into neural ectoderm germ layer.
References 1. "SOX2". NCBI.
2. Johansson H, Simonsson S (2010) Aging. (11): 815–822.
3. Thomson M., Liu S.J., Zou L.N., Smith Z., Meissner A., Ramanathan S. (2011) Cell. 145(6): 875–889.

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  FITC (Fluorescein)
Overview:

  • Excellent fluorescence quantum yield
  • High rate of photobleaching
  • Good solubility in water
  • Broad emission spectrum
  • pH dependent spectra
  • Molecular formula: C20H12O5
  • Molar mass: 332.3 g/mol

FITC-Fluorescent-conjugate

FITC Fluorescein Fluorophore Excitation and Emission SpectraOptical Properties:

λex = 494 nm

λem = 520 nm

εmax = 7.3×104

Φf = 0.92

τfl = 5.0 ns

Brightness = 67.2

Laser = 488 nm

Filter set = FITC

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。