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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-SOX2 Antibody/SPC-1287D/100-µl
商品详细StressMarq/Anti-SOX2 Antibody/SPC-1287D/100-µl
StressMarq/Anti-SOX2 Antibody/SPC-1287D/100-µl
StressMarq/Anti-SOX2 Antibody/SPC-1287D/100-µl
商品编号: SPC-1287D
市场价: ¥5100.00
美元价: 3060.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSOX2Antibody
Description

RabbitAnti-HumanSOX2Polyclonal

SpeciesReactivityHuman,Mouse,Rat
ApplicationsWB,IHC,ICC/IF
AntibodyDilutionWB(1:2000),IHC(1:200),ICC/IF(1:500);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAsynthesizedpeptidederivedfromhumanSOX2
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationAffinityPurified
ClonalityPolyclonal
IsotypeIgG
SpecificityDetects~34kDa,endogenouslevelsoftotalSOX2
CiteThisProductStressMarqBiosciencesCat#SPC-1287,RRID:AB_2712971
CertificateofAnalysisA1:1000dilutionofSPC-1287wassufficientfordetectionofSOX2in10µgofHT29celllysatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesSOX2Antibody,SRY(sexdeterminingregionY)box2Antibody,SRYrelatedHMGbox2Antibody,SRY-box2Antibody,ANOP3Antibody,ysbAntibody
ResearchAreasEmbryonicStemCells,ESCIntracellularMarkers,GermlineStemCells,StemCells
CellularLocalizationNucleus
AccessionNumberNP_003097.1
GeneID6657
SwissProtP48431
ScientificBackgroundTheSOX(SRY-boxcontaininggene)genefamilyencodesagroupoftranscriptionfactorsdefinedbytheconservedhighmotilitygroup(HMG)DNA-bindingdomain.TheyareinvolvedintheregulationofembryonicdevelopmentwhenitformscomplexeswithOct4andNanog.VaryinglevelsofSox2canaffectthedeterminationofcellfate.Sox2inhibitsdifferentiationintothemesendodermgermlayerandpromotesdifferentiationintoneuralectodermgermlayer.
References1."SOX2".NCBI.
2.JohanssonH,SimonssonS(2010)Aging.(11):815–822.
3.ThomsonM.,LiuS.J.,ZouL.N.,SmithZ.,MeissnerA.,RamanathanS.(2011)Cell.145(6):875–889.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。