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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > STRESS MARQ/SKF-96365/SIH-305-25MG/25MG
商品详细STRESS MARQ/SKF-96365/SIH-305-25MG/25MG
STRESS MARQ/SKF-96365/SIH-305-25MG/25MG
STRESS MARQ/SKF-96365/SIH-305-25MG/25MG
商品编号: SIH-305-25MG
市场价: ¥6780.00
美元价: 4068.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSKF-96365
Description

TRPCchannelblocker

Purity>98%
CASNo.130495-35-1
MolecularFormulaC22H26N2O3.HCl
MolecularWeight402.92

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto100mMinwater
SourceSynthetic
AppearanceWhitesolid
SMILESCOC1=CC=C(C=C1)CCCOC(CN2C=CN=C2)C3=CC=C(C=C3)OC.Cl
InChIInChI=1S/C22H26N2O3.ClH/c1-25-20-9-5-18(6-10-20)4-3-15-27-22(16-24-14-13-23-17-24)19-7-11-21(26-2)12-8-19;/h5-14,17,22H,3-4
InChIKeyFWLPKVQUECFKSW-UHFFFAOYSA-N
SafetyPhrasesClassification:Irritant.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionHazardPhrases:H315-H319-H335PrecautionaryPhrases:P261-P305+P351+P338
CiteThisProductSKF-96365(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-305)

BIOLOGicalDescription

AlternativeNames1-{2-(4-Methoxyphenyl)-2-[3-(4-methoxyphenyl)propoxy]ethyl}-1H-imidazolehydrochloride(1:1)
ResearchAreasIonChannels,Neuroscience,TransientReceptorPotentialChannels
PubChemID104956
ScientificBackgroundSKF-96365isaselectiveinhibitorofreceptormediatedCa2+entryandvoltage-gatedCa2+entry(1).IthasalsobeenshownoinhibitcytochromeP-450mediatedreactions(1,2),andreversIBLyactivatesnon-selectivecationchannelsinhumanendotherlialcells(1,3).
References1.LeisH.J.,etal.(1995)BrJPharmacol.114(3):598-601.
2.SheetsJ.J.,MasonJ.I.,WiseC.A.andEastabrookR.W.(1986)BiochemPharmacol.35:487-491.
3.SchwarzG.,DroogmansG.andNiliusB.(1994)CellCalcium.15:45-54.

ProductImages

<p>Chemical structure of SKF-96365 (SIH-305), a TRPC channel blocker. CAS #: 130495-35-1. Molecular Formula: C22H26N2O3.HCl. Molecular Weight: 402.92 g/mol.</p>

ChemicalstructureofSKF-96365(SIH-305),aTRPCchannelblocker.CAS#:130495-35-1.MolecularFormula:C22H26N2O3.HCl.MolecularWeight:402.92g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。