StressMarq/Sirtinol/SIH-360-5MG/5-mg
商品编号：
SIH-360-5MG
市场价：
¥1960.00
美元价：
1176.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Sirtinol |
| Description | SIRTinhibitor |
| Purity | >98% |
| CASNo. | 410536-97-9 |
| MolecularFormula | C26H22N2O2 |
| MolecularWeight | 394.47 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinDMSO |
| Source | Synthetic |
| Appearance | Off-whitetoyellowcrystals |
| SMILES | [[email protected]@H](NC(=O)C1=CC=CC=C1NC=C/3C2=CC=CC=C2C=CC3=O)(C4=CC=CC=C4)C |
| InChI | InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,27H,1H3,(H,28,30)/b23-17- |
| InChIKey | YUGODMKHHCZZOI-QJOMJCCJSA-N |
| SafetyPhrases | Classification:Caution.Substancenotyetfullytested.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-Avoidcontactwithskinandeyes |
| CiteThisProduct | Sirtinol(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-360) |
BIOLOGicalDescription
| AlternativeNames | 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide |
| ResearchAreas | CellSignaling,Epigenetics |
| PubChemID | 5717148 |
| ScientificBackground | Cell-permeable,selectivesirtuindeacetylaseinhibitor(IC50valuesare38,68and131µMatSIRT2,Sir2pandSIRT1respectively)thathasnoeffectonHDAC1activity.SignificantlydecreasesgrowthandviABIlityofPCaandHEK293Tcellsinvitro. |
| References | 1.GrozingerCM.,etal(2001)J.Biol.Chem.276:38837. 2.MaiA.,etal(2005)J.Med.Chem.48:7789. 3.KahyoT.,etal(2008)J.Pharmacol.Sci.108:364. 4.Jung-HynesB.,etal(2009)J.Biol.Chem.284:3823. |
ProductImages
ChemicalstructureofSirtinol(SIH-360),aSIRTinhibitor.CAS#:410536-97-9.MolecularFormula:C26H22N2O2.MolecularWeight:394.47g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
