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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-SIK1 Antibody (pThr182)/SPC-1082D-A655/100-µl
商品详细StressMarq/Anti-SIK1 Antibody (pThr182)/SPC-1082D-A655/100-µl
StressMarq/Anti-SIK1 Antibody (pThr182)/SPC-1082D-A655/100-µl
StressMarq/Anti-SIK1 Antibody (pThr182)/SPC-1082D-A655/100-µl
商品编号: SPC-1082D-A655
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name SIK1 Antibody (pThr182)
Description

Rabbit Anti-Human SIK1 (pThr182) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Thr182 of human SIK1 (AA179-185)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 84.902 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1082, RRID: AB_2709875
Certificate of Analysis A 1:250 dilution of SPC-1082 was sufficient for detection of SIK1 (pThr182) in 10 µg of 293T cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names SNF1LK Antibody, KID2 Antibody, MSK Antibody, myocardial SNF1 like kinase Antibody, QIK Antibody, Qin-induced kinase Antibody, Salt inducible kinase 1 Antibody, Salt-inducible protein kinase 1 Antibody, Serine threonine protein kinase SNF1 like kinase 1 Antibody, Serine threonine protein kinase SNF1LK Antibody, Serine/threonine-protein kinase SIK1 Antibody, Serine/threonine-protein kinase SNF1-like kinase 1 Antibody, Serine/threonine-protein kinase SNF1LK Antibody, SIK-1 Antibody, SIK1 Antibody, SIK1_HUMAN Antibody, SNF1 like kinase Antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_775490
Gene ID 102724428
Swiss Prot P57059
Scientific Background SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.

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 ATTO 655
Overview:

  • High fluorescence yield
  • High thermal and photostability
  • Excellent ozone resistance
  • Quenched by electron donors
  • Very hydrophilic
  • Good solubility in polar solvents
  • Zwitterionic dye
  • Molar Mass: 634 g/mol

ATTO 655 Datasheet

ATTO 655 Fluorophore Absorption and Emission SpectrumOptical Properties:

λex = 663 nm

λem = 684 nm

εmax = 1.25×105

Φf = 0.30

τfl = 1.8 ns

Brightness = 37.5

Laser = 633 – 647 nm

Filter set = Cy®5

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。