StressMarq/SC 514/SIH-475-50MG/50-mg
商品编号:
SIH-475-50MG
市场价:
¥5900.00
美元价:
3540.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | SC514 |
Description | IKK-2kinaseinhibitor |
Purity | >98%(TLC) |
CASNo. | 354812-17-2 |
MolecularFormula | C9H8N2OS2 |
MolecularWeight | 224.3 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | SolubleinDMSO(>25mg/ml) |
Source | Synthetic |
Appearance | Yellowsolid |
SMILES | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N |
InChI | InChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12) |
InChIKey | BMUACLADCKCNKZ-UHFFFAOYSA-N |
SafetyPhrases | Classification:Acutetoxicity,Oral(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301ToxicifswallowedPrecautionarystatements:P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician |
CiteThisProduct | SC514(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-475) |
BIOLOGicalDescription
AlternativeNames | 4-Amino-[2",3"-bithiophene]-5-carboxamide |
ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
PubChemID | 2807869 |
ScientificBackground | SC514isaselectiveandreversibleinhibitorofIκBkinase2/IKKβ(IKK-2).Ithasbeenshowntodisplays>10-foldselectivityover28otherkinasesincludingJNK,p38,MK2andERK.SC-514exhibitsanti-inflammatoryproperties.SC514iscellpermeable. |
References | 1.KishoreN.,etal.(2003)J.Biol.Chem.278(35):32861–32871. 2.BaxterA.,etal.(2004)BioorganicMed.Chem.Letters.14(11):2817–2822. |
ProductImages
ChemicalstructureofSC514(SIH-475),aIKK-2kinaseinhibitor.CAS#:354812-17-2.MolecularFormula:C9H8N2OS2.MolecularWeight:224.3g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。