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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/SC 514/SIH-475-10MG/10-mg
商品详细StressMarq/SC 514/SIH-475-10MG/10-mg
StressMarq/SC 514/SIH-475-10MG/10-mg
StressMarq/SC 514/SIH-475-10MG/10-mg
商品编号: SIH-475-10MG
市场价: ¥1500.00
美元价: 900.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSC514
Description

IKK-2kinaseinhibitor

Purity>98%(TLC)
CASNo.354812-17-2
MolecularFormulaC9H8N2OS2
MolecularWeight224.3

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO(>25mg/ml)
SourceSynthetic
AppearanceYellowsolid
SMILESC1=CSC=C1C2=CC(=C(S2)C(=O)N)N
InChIInChI=1S/C9H8N2OS2/c10-6-3-7(5-1-2-13-4-5)14-8(6)9(11)12/h1-4H,10H2,(H2,11,12)
InChIKeyBMUACLADCKCNKZ-UHFFFAOYSA-N
SafetyPhrasesClassification:Acutetoxicity,Oral(Category3)SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H301ToxicifswallowedPrecautionarystatements:P301+P310IFSWALLOWED:ImmediatelycallaPOISONCENTERordoctor/physician
CiteThisProductSC514(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-475)

BIOLOGicalDescription

AlternativeNames4-Amino-[2",3"-bithiophene]-5-carboxamide
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID2807869
ScientificBackgroundSC514isaselectiveandreversibleinhibitorofIκBkinase2/IKKβ(IKK-2).Ithasbeenshowntodisplays>10-foldselectivityover28otherkinasesincludingJNK,p38,MK2andERK.SC-514exhibitsanti-inflammatoryproperties.SC514iscellpermeable.
References1.KishoreN.,etal.(2003)J.Biol.Chem.278(35):32861–32871.
2.BaxterA.,etal.(2004)BioorganicMed.Chem.Letters.14(11):2817–2822.

ProductImages

<p>Chemical structure of SC 514 (SIH-475), a IKK-2 kinase inhibitor. CAS #: 354812-17-2. Molecular Formula: C9H8N2OS2. Molecular Weight: 224.3 g/mol.</p>

ChemicalstructureofSC514(SIH-475),aIKK-2kinaseinhibitor.CAS#:354812-17-2.MolecularFormula:C9H8N2OS2.MolecularWeight:224.3g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。