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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/SB431542/SIH-511-25MG/25-mg
商品详细StressMarq/SB431542/SIH-511-25MG/25-mg
StressMarq/SB431542/SIH-511-25MG/25-mg
StressMarq/SB431542/SIH-511-25MG/25-mg
商品编号: SIH-511-25MG
市场价: ¥9500.00
美元价: 5700.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameSB431542
Description

ALK4,5and7kinaseinhibitor

Purity>98%(HPLC)
CASNo.301836-41-9
MolecularFormulaC22H16N4O3
MolecularWeight384.4

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleto10mMinethanolandto100mMinDMSO
SourceSynthetic
AppearanceYellowsolid
SMILESC1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
InChIInChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
InChIKeyFHYUGAJXYORMHI-UHFFFAOYSA-N
SafetyPhrasesClassification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductSB431542(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-511)

BIOLOGicalDescription

AlternativeNamesSB431542,4-(5-Benzol[1,3]dioxol-5-yl-4-pyrldin-2-yl-1H-imidazol-2-yl)-benzamidehydrate,4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamidehydrate,4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]-benzamidehydrate
ResearchAreasCancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors
PubChemID4521392
ScientificBackgroundSB431542isapotentandselectiveinhibitorofthetransforminggrowthfactor-β(TGF-β)typeIreceptor,activinreceptor-likekinases.IthasbeenshowntoinhibitALK4,5,and7.
References1.LapingN.J.,etal.(2002)Mol.Pharm.62(1):58–64.

ProductImages

<p>Chemical structure of SB431542 (SIH-511), a ALK4,5 and 7 kinase inhibitor. CAS #: 301836-41-9. Molecular Formula: C22H16N4O3. Molecular Weight: 384.4 g/mol.</p>

ChemicalstructureofSB431542(SIH-511),aALK4,5and7kinaseinhibitor.CAS#:301836-41-9.MolecularFormula:C22H16N4O3.MolecularWeight:384.4g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。