StressMarq/SB216763/SIH-510-25MG/25-mg
商品编号：
SIH-510-25MG
市场价：
¥7000.00
美元价：
4200.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | SB216763 |
| Description | GSK-3kinaseinhibitor |
| Purity | >98%(TLC) |
| CASNo. | 280744-09-4 |
| MolecularFormula | C19H12Cl2N2O2 |
| MolecularWeight | 371.2 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(>25mg/ml) |
| Source | Synthetic |
| Appearance | Orangesolid |
| SMILES | CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl |
| InChI | InChI=1S/C19H12Cl2N2O2/c1-23-9-13(11-4-2-3-5-15(11)23)17-16(18(24)22-19(17)25)12-7-6-10(20)8-14(12)21/h2-9H,1H3,(H,22,24,25) |
| InChIKey | JCSGFHVFHSKIJH-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Skinirritation(Category2),H315Eyeirritation(Category2A),H319Specifictargetorgantoxicity-singleexposure(Category3),Respiratorysystem,H335SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315Causesskinirritation.H319Causesseriouseyeirritation.H335Maycauserespiratoryirritation.Precautionarystatements:P261Avoidbreathingdust/fume/gas/mist/vapours/spray.P264Washskinthoroughlyafterhandling.P271Useonlyoutdoorsorinawell-ventilatedarea.P280Wearprotectivegloves/eyeprotection/faceprotection.P302+P352IFONSKIN:Washwithplentyofsoapandwater.P304+P340IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P305+P351+P338IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P312CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P321Specifictreatment(seesupplementalfirstaidinstructionsonthislabel).P332+P313Ifskinirritationoccurs:Getmedicaladvice/attention.P337+P313Ifeyeirritationpersists:Getmedicaladvice/attention.P362Takeoffcontaminatedclothingandwashbeforereuse.P403+P233Storeinawell-ventilatedplace.Keepcontainertightlyclosed.P405Storelockedup.P501Disposeofcontents/containertoanapprovedwastedisposalplant. |
| CiteThisProduct | SB216763(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-510) |
BIOLOGicalDescription
| AlternativeNames | SB216763,3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 176158 |
| ScientificBackground | SB216763isapotentandselectiveglycogensynthasekinase-3(GSK-3)inhibitor.ItinhibitsbothhumanGSK-3αandGSK-3β.SB216763hasbeenshowntostimulateglycogensynthesisinhumanlivercellsandmimicotheractionsofinsulin.SB216763iscell-permeableandATP-competitive. |
| References | 1.CulbertA.A.,etal.(2001)FEBSLetters.507(3):288–294. 2.CoghlanM.P.,etal.(2000)Chem.Biol.7(10):793–803. |
ProductImages
ChemicalstructureofSB216763(SIH-510),aGSK-3kinaseinhibitor.CAS#:280744-09-4.MolecularFormula:C19H12Cl2N2O2.MolecularWeight:371.2g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
