StressMarq/SAHA (Vorinostat)/SIH-359-50MG/50-mg
商品编号:
SIH-359-50MG
市场价:
¥1140.00
美元价:
684.00
产品分类:
酸碱缓冲液
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
Overview:
ProductName | SAHA(Vorinostat) |
Description | HDACinhibitor |
Purity | >98%(TLC);NMR(Conforms) |
CASNo. | 149647-78-9 |
MolecularFormula | C14H20N2O3 |
MolecularWeight | 264.3 |
Properties
StorageTemperature | -20ºC |
ShippingTemperature | ShippedAmbient |
ProductType | Inhibitor |
Solubility | Solublein50mg/mlDMSO,or2mg/mlEthanol |
Source | Synthetic |
Appearance | WhiteSolid |
SMILES | C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO |
InChI | InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h4-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18) |
InChIKey | WAEXFXRVDQXREF-UHFFFAOYSA-N |
SafetyPhrases | Classification:Harmful-Maybeharmfulifinhaled,swallowed,orabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionS24/25-AvoidcontactwithskinandeyesHazardStatements:H341-H360(SUSPectedofcausinggeneticdefects)PrecautionaryStatements:P201-P281-P308+P313 |
CiteThisProduct | SAHA(Vorinostat)(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-359) |
BIOLOGicalDescription
AlternativeNames | Suberoylanilide-hydroxamicacid;Vorinostat;N-Hydroxy-N"-phenyloctanediamide |
ResearchAreas | Cancer,CellSignaling,Epigenetics |
PubChemID | 5311 |
ScientificBackground | Potentandselectivehistonedeacetylaseinhibitor.Inducesapoptosisinavarietyoftumorcelllines.SynergizeswithkinaseinhibitorstokillCNStumorcells.Cellpermeable. |
References | 1.VranaJ.A.,etal.,(1999)Oncogene.18:7016. 2.ButlerL.M.,etal.,(2002)Proc.Natl.Acad.Sci.USA.99:11700. 3.TangY.,etal.,(2012)CancerBiol.Ther.201213(7):567-574. |
ProductImages
ChemicalstructureofSAHA(Vorinostat)(SIH-359),aHDACinhibitor.CAS#:149647-78-9.MolecularFormula:C14H20N2O3.MolecularWeight:264.3g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。