StressMarq/Ruxolitinib/SIH-509-25MG/25MG
商品编号：
SIH-509-25MG
市场价：
¥10000.00
美元价：
6000.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| Product Name | Ruxolitinib |
| Description | JAK kinase inhibitor |
| Purity | >98% |
| CAS No. | 941678-49-5 |
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.4 |
Properties
| Storage Temperature | -20ºC |
| Shipping Temperature | Shipped Ambient |
| Product Type | Inhibitor |
| Solubility | Soluble in DMSO (25 mg/ml) or EtOH (~15 mg/ml) |
| Source | Synthetic |
| Appearance | Off-white solid |
| SMILES | C1CCC(C1)[[email protected]@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
| InChI | InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1 |
| InChIKey | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| Safety Phrases | Classification: Skin Corrosion/Irritation, Category 2 Serious Eye Damage/Eye Irritation, Category 1 Danger Target Organ Systemic Toxicity (repeated exposure), Category 2 Toxic To Reproduction, Category 2 Warning Acute Toxicity: Oral, Category 4Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.Hazard statements: H315: Causes skin irritation. H318: Causes serious eye damage H373: May cause damage to organs through prolonged or repeated exposure. H361: Suspected of damaging fertility or the unborn child. H302: Harmful if swallowed.Precautionary statements: P264: Wash hands thoroughly after handling. P280: Wear protective gloves/clothing and eye/face protection as specified by the manufacturer/supplier or the competent authority. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P302+352: IF ON SKIN: Wash with plenty of soap and water. P332+313: If skin irritation occurs, get medical advice/attention. P362: Take off contaminated clothing and wash before re-use. P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical attentiodvice if you feel unwell. P308+313: IF exposed or concerned: Get medical attentiodvice. P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P330: Rinse mouth. |
| Cite This Product | Ruxolitinib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-509) |
Biological Description
| Alternative Names | (3R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| Research Areas | Cancer, Apoptosis, Cancer Growth Inhibitors, Cell Signaling, Tyrosine Kinase Inhibitors |
| PubChem ID | 25126798 |
| Scientific Background | Ruxolitinib is a Janus-associated kinases (JAK) inhibitor, which specifically inhibits JAK1 and JAK3. JAKs are known to active the signaling of certain growth factor receptors and cytokines. |
| References | 1. Aittomäki S., & Pesu M. (2014) Basic & Clin. Pharm.Toxic. 114(1): 18–23. |
Product Images
Chemical structure of Ruxolitinib (SIH-509), a JAK kinase inhibitor. CAS #: 941678-49-5. Molecular Formula: C17H18N6. Molecular Weight: 306.4 g/mol.
Product Citations (0)
Currently there are no citations for this product.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
