StressMarq/Ruxolitinib/SIH-509-5MG/5-mg
商品编号：
SIH-509-5MG
市场价：
¥3100.00
美元价：
1860.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Ruxolitinib |
| Description | JAKkinaseinhibitor |
| Purity | >98% |
| CASNo. | 941678-49-5 |
| MolecularFormula | C17H18N6 |
| MolecularWeight | 306.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO(25mg/ml)orEtOH(~15mg/ml) |
| Source | Synthetic |
| Appearance | Off-whitesolid |
| SMILES | C1CCC(C1)[[email protected]@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
| InChI | InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1 |
| InChIKey | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| SafetyPhrases | Classification:SkinCorrosion/Irritation,Category2SeriousEyeDamage/EyeIrritation,Category1DangerTargetOrganSystemicToxicity(repeatedexposure),Category2ToxicToReproduction,Category2WarningAcuteToxicity:Oral,Category4SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315:Causesskinirritation.H318:CausesseriouseyedamageH373:Maycausedamagetoorgansthroughprolongedorrepeatedexposure.H361:SUSPectedofdamagingfertilityortheunbornchild.H302:Harmfulifswallowed.Precautionarystatements:P264:Washhandsthoroughlyafterhandling.P280:Wearprotectivegloves/clothingandeye/faceprotectionasspecifiedbythemanufacturer/supplierorthecompetentauthority.P260:Donotbreathedust/fume/gas/mist/vapours/spray.P201:Obtainspecialinstructionsbeforeuse.P202:Donothandleuntilallsafetyprecautionshavebeenreadandunderstood.P281:Usepersonalprotectiveequipmentasrequired.P302+352:IFONSKIN:Washwithplentyofsoapandwater.P332+313:Ifskinirritationoccurs,getmedicaladvice/attention.P362:Takeoffcontaminatedclothingandwashbeforere-use.P305+351+338:IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P310:ImmediatelycallaPOISONCENTERordoctor/physician.P314:Getmedicalattentiodviceifyoufeelunwell.P308+313:IFexposedorconcerned:Getmedicalattentiodvice.P301+312:IFSWALLOWED:CallaPOISONCENTERordoctor/physicianifyoufeelunwell.P330:Rinsemouth. |
| CiteThisProduct | Ruxolitinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-509) |
BIOLOGicalDescription
| AlternativeNames | (3R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,CellSignaling,TyrosineKinaseInhibitors |
| PubChemID | 25126798 |
| ScientificBackground | RuxolitinibisaJanus-associatedkinases(JAK)inhibitor,whichspecificallyinhibitsJAK1andJAK3.JAKsareknowntoactivethesignalingofcertaingrowthfactorreceptorsandcytokines. |
| References | 1.AittomäkiS.,&PesuM.(2014)Basic&Clin.Pharm.Toxic.114(1):18–23. |
ProductImages
ChemicalstructureofRuxolitinib(SIH-509),aJAKkinaseinhibitor.CAS#:941678-49-5.MolecularFormula:C17H18N6.MolecularWeight:306.4g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
