StressMarq/Anti-RUNX2 Antibody/SPC-1311D-STR/100-µl-免疫在线蚂蚁淘旗下平台

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StressMarq/Anti-RUNX2 Antibody/SPC-1311D-STR/100-µl

商品编号： SPC-1311D-STR

品牌： StressMarq Biosciences

市场价： ¥6000.00

美元价： 3600.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

Product Name RUNX2 Antibody

Description

Rabbit Anti-Human RUNX2 Polyclonal

Species Reactivity Human, Mouse

Applications WB, IHC, ICC/IF

Antibody Dilution WB (1:1000), IHC (1:200), ICC/IF (1:200); optimal dilutions for assays should be determined by the user.

Host Species Rabbit

Immunogen Species Human

Immunogen A synthesized peptide derived from RUNX2

Conjugates

Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer	PBS pH 7.4, 50% glycerol, 150mM NaCl, 0.02% sodium azide
Storage Temperature	-20ºC
Shipping Temperature	Blue Ice or 4ºC
Purification	Affinity Purified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects ~56kDa, endogenous levels of total RUNX2
Cite This Product	StressMarq Biosciences Cat# SPC-1311, RRID: AB_2713385
Certificate of Analysis	A 1:1000 dilution of SPC-1311 was sufficient for detection of RUNX2 in 10 µg of MC3T3-E1 cell lysates by ECL immunoblot analysis using Goat Anti-Rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names	Acute myeloid leukemia 3 protein Antibody, Alpha subunit 1 Antibody, AML3 Antibody, CBF alpha 1 Antibody, CBF-alpha-1 Antibody, CBFA1 Antibody, CCD Antibody, CCD1 Antibody, Cleidocranial dysplasia 1 Antibody, Core binding factor Antibody, Core binding factor runt domain alpha subunit 1 Antibody, Core binding factor subunit alpha 1 Antibody, Core-binding factor subunit alpha-1 Antibody, MGC120022 Antibody, MGC120023 Antibody, Oncogene AML 3 Antibody, Oncogene AML-3 Antibody, OSF 2 Antibody, OSF-2 Antibody, OSF2 Antibody, Osteoblast specific transcription factor 2 Antibody, Osteoblast-specific transcription factor 2 Antibody, OTTHUMP00000016533 Antibody, PEA2 alpha A Antibody, PEA2-alpha A Antibody, PEA2aA Antibody, PEBP2 alpha A Antibody, PEBP2-alpha A Antibody, PEBP2A1 Antibody, PEBP2A2 Antibody, PEBP2aA Antibody, PEBP2aA1 Antibody, Polyomavirus enhancer binding protein 2 alpha A subunit Antibody, Polyomavirus enhancer-binding protein 2 alpha A subunit Antibody, Runt domain Antibody, Runt related transcription factor 2 Antibody, Runt-related transcription factor 2 Antibody, RUNX2 Antibody, RUNX2_HUMAN Antibody, SL3 3 enhancer factor 1 alpha A subunit Antibody, SL3-3 enhancer factor 1 alpha A subunit Antibody, SL3/AKV core binding factor alpha A subunit Antibody, SL3/AKV core-binding factor alpha A subunit Antibody
Cellular Localization	Nucleus
Accession Number	NP_001019801.3
Gene ID	860
Swiss Prot	Q13950
Scientific Background	RUNX2 (Runt-related transcription Factor) is a transcription factor that binds to its canonical consensus sequence 5’- PYGPYGGT-3’ in a number of promoters and enhancers. Through interaction with Twist 1 and Twist 2, RUNX2 regulates osteocalcin transcription, following parathyroid hormone signaling for bone loss repair. Ossification in skeletal formation is also partially regulated through RUNX2. Essentially, this transcription factor is responsible for many developmental and repair mechanisms in bone and collagen. Mutations in Cbfa1/Runx2 are associated with the disease Cleidocranial dysostosis.
References	1. Green RE et al. (2010) Science 328 (5979): 710–22. 2. Pockwinse SM et al. (2011) Journal of Cellular Physiology 226 (5): 1383–9. 3. Lian JB. (2004) Critical Reviews in Eukaryotic Gene Expression 14 (1-2): 1–41.

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Streptavidin

Properties:

Homo-tetrameric protein purified from Streptomyces avidinii which binds four biotin molecules with extremely high affinity
Molecular weight: 53 kDa
Formula: C₁₀H₁₆N₂O₃S
Applications: Western blot, immunohistochemistry, and ELISA

Streptavidin Datasheet

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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