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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Anti-RSK1 Antibody (pThr573)/SPC-1078D-HRP/100-µl
商品详细StressMarq/Anti-RSK1 Antibody (pThr573)/SPC-1078D-HRP/100-µl
StressMarq/Anti-RSK1 Antibody (pThr573)/SPC-1078D-HRP/100-µl
StressMarq/Anti-RSK1 Antibody (pThr573)/SPC-1078D-HRP/100-µl
商品编号: SPC-1078D-HRP
市场价: ¥6600.00
美元价: 3960.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameRSK1Antibody(pThr573)
Description

RabbitAnti-HumanRSK1(pThr573)Polyclonal

SpeciesReactivityHuman
ApplicationsWB,AM
AntibodyDilutionWB(1:250);optimaldilutionsforassaysshouldbedeterminedbytheuser.
HostSpeciesRabbit
ImmunogenSpeciesHuman
ImmunogenAphospho-specificpeptidecorrespondingtoresiduessurroundingThr573ofhumanRSK1(AA570-576)
ConjugatesAlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBufferPBSpH7.4,50%glycerol,0.025%Thimerosal
StorageTemperature-20ºC
ShippingTemperatureBlueIceor4ºC
PurificationPeptideAffinityPurified
ClonalityPolyclonal
SpecificityDetects82.723kDa.
CiteThisProductStressMarqBiosciencesCat#SPC-1078,RRID:AB_2709803
CertificateofAnalysisA1:250dilutionofSPC-1078wassufficientfordetectionofRSK1(pThr573)in10µgofHeLacelllysatebyECLimmunoblotanalysisusinggoatanti-rabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNamesRPS6KA1Antibody,RSK1Antibody,RSK1p90Antibody,RSKAntibody,RSK-1Antibody,S6Kalpha1Antibody,S6K-alpha-1Antibody,90kDaribosomalproteinS6kinase1Antibody,RibosomalproteinS6kinase90kD1Antibody,RibosomalproteinS6kinase90kDapolypeptide1Antibody,RibosomalproteinS6kinasealpha1Antibody,RibosomalproteinS6kinasealpha-1Antibody,RibosomalproteinS6kinasepolypeptide1Antibody,RibosomalS6kinase1Antibody,RPS6K1alphaAntibody,rps6kaAntibody,EC2.7.11.1Antibody,HU1Antibody,HU1Antibody,KS6A1_HUMANAntibody,MAPkinaseactivatedproteinkinase1aAntibody,MAPkinase-activatedproteinkinase1aAntibody,MAPK-activatedproteinkinase1aAntibody,MAPKAPkinase1aAntibody,MAPKAPK-1aAntibody,MAPKAPK1AAntibody,MGC79981Antibody,Mitogen-activatedproteinkinase-activatedproteinkinase1AAntibody,OTTHUMP00000004113Antibody,p90RSK1Antibody,p90-RSK1Antibody,p90rskAntibody,p90RSK1Antibody,p90S6KAntibody,pp90RSK1Antibody
CellularLocalizationCytoplasm,Nucleus
AccessionNumberNP_002944
GeneID6195
SwissProtQ15418
ScientificBackgroundRSK1isaRSK(ribosomalS6kinase)familyofserine/threoninekinases.RSK1contains2nonidenticalkinasecatalyticdomains.RSK1isknownphosphorylatesvarioussubstrates,includingmembersofthemitogen-activatedkinase(MAPK)signallingpathway--apro-growth/anti-apoptoticpathway,asitwillactivateCREB,whichinturnwillupregulateexpressionofcylin-Dandc-Myc.Activationofthispathwayiscommoninvarioustypesoftumours.Insomecases,suchbreastandprostatecancer,upreguationofRSKhasbeenshowninsomepatients.

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HRP(HorserADIshperoxidase)

Properties:

  • Enzymaticactivityisusedtoamplifyweaksignalsandincreasevisibilityofatarget
  • Readilycombineswithhydrogenperoxide(H2O2)toformHRP-H2O2complexwhichcanoxidizevarioushydrogendonors
  • Catalyzestheconversionof:
    • Chromogenicsubstrates(e.g.TMB,DAB,ABTS)intocolouredproducts
    • Chemiluminescentsubstrates(e.g.luminolandisoluminol)intolightemittingproductsviaenhancedchemiluminescence(ECL)
    • Fluorogenicsubstrates(e.g.tyramine,homovanillicacid,and4-hydroxyphenylaceticacid)intofluorescentproducts
  • Highturnoverrateenablesrapidgenerationofastrongsignal
  • 44kDaglycoprotein
  • Extinctioncoefficient:100(403nm)
  • Applications:Westernblot,immunohistochemistry,andELISA

HRPDatasheet

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。