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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > 应力MARQ/抗RSK1抗体(pSer380)/SPC-1077D-A594/100-µl
商品详细应力MARQ/抗RSK1抗体(pSer380)/SPC-1077D-A594/100-µl
应力MARQ/抗RSK1抗体(pSer380)/SPC-1077D-A594/100-µl
应力MARQ/抗RSK1抗体(pSer380)/SPC-1077D-A594/100-µl
商品编号: SPC-1077D-A594
市场价: ¥6840.00
美元价: 4104.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

Product Name RSK1 Antibody (pSer380)
Description

Rabbit Anti-Human RSK1 (pSer380) Polyclonal

Species Reactivity Human
Applications WB, AM
Antibody Dilution WB (1:250); optimal dilutions for assays should be determined by the user.
Host Species Rabbit
Immunogen Species Human
Immunogen A phospho-specific peptide corresponding to residues surrounding Ser380 of human RSK1 (AA377-383)
Conjugates Alkaline Phosphatase, APC, ATTO 390, ATTO 488, ATTO 565, ATTO 594, ATTO 633, ATTO 655, ATTO 680, ATTO 700, Biotin, FITC, HRP, PE/ATTO 594, PerCP, RPE, Streptavidin, Unconjugated

Properties

Storage Buffer PBS pH7.4, 50% glycerol, 0.025% Thimerosal
Storage Temperature -20ºC
Shipping Temperature Blue Ice or 4ºC
Purification Peptide Affinity Purified
Clonality Polyclonal
Specificity Detects 82.723 kDa.
Cite This Product StressMarq Biosciences Cat# SPC-1077, RRID: AB_2709785
Certificate of Analysis A 1:250 dilution of SPC-1077 was sufficient for detection of RSK1 (pSer380) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

Biological Description

Alternative Names RPS6KA1 Antibody, RSK 1 Antibody, RSK 1 p90 Antibody, RSK Antibody, RSK-1 Antibody, S6K alpha 1 Antibody, S6K-alpha-1 Antibody, 90 kDa ribosomal protein S6 kinase 1 Antibody, Ribosomal protein S6 kinase 90kD 1 Antibody, Ribosomal protein S6 kinase 90kDa polypeptide 1 Antibody, Ribosomal protein S6 kinase alpha 1 Antibody, Ribosomal protein S6 kinase alpha-1 Antibody, Ribosomal protein S6 kinase polypeptide 1 Antibody, Ribosomal S6 kinase 1 Antibody, RPS6K1 alpha Antibody, rps6ka Antibody, EC 2.7.11.1 Antibody, HU 1 Antibody, HU1 Antibody, KS6A1_HUMAN Antibody, MAP kinase activated protein kinase 1a Antibody, MAP kinase-activated protein kinase 1a Antibody, MAPK-activated protein kinase 1a Antibody, MAPKAP kinase 1a Antibody, MAPKAPK-1a Antibody, MAPKAPK1A Antibody, MGC79981 Antibody, Mitogen-activated protein kinase-activated protein kinase 1A Antibody, OTTHUMP00000004113 Antibody, p90 RSK1 Antibody, p90-RSK 1 Antibody, p90rsk Antibody, p90RSK1 Antibody, p90S6K Antibody, pp90RSK1 Antibody
Cellular Localization Cytoplasm, Nucleus
Accession Number NP_002944
Gene ID 6195
Swiss Prot Q15418
Scientific Background RSK1 is a RSK (ribosomal S6 kinase) family of serine/threonine kinases. RSK1 contains 2 nonidentical kinase catalytic domains. RSK1 is known phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway -- a pro-growth/anti-apoptotic pathway, as it will activate CREB, which in turn will upregulate expression of cylin-D and c-Myc. Activation of this pathway is common in various types of tumours. In some cases, such breast and prostate cancer, upreguation of RSK has been shown in some patients.

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 ATTO 594
Overview:

  • High fluorescence yield
  • High photostability
  • Very hydrophilic
  • Excellent solubility in water
  • Very little aggregation
  • New dye with net charge of -1
  • Molar Mass: 1137 g/mol

ATTO 594 Datasheet

 ATTO 594 Fluorophore Excitation and Emission SpectrumOptical Properties:

λex = 601 nm

λem = 627 nm

εmax = 1.2×105

Φf = 0.85

τfl = 3.5 ns

Brightness = 102

Laser = 594 nm

Filter set = Texas Red®

 

品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。