STRESTMARQ/Rottlerin/SIH-394-10MG/10MG
商品编号：
SIH-394-10MG
市场价：
¥1440.00
美元价：
864.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Rottlerin |
| Description | Autophagyinducer |
| Purity | >98% |
| CASNo. | 82-08-6 |
| MolecularFormula | C30H28O8 |
| MolecularWeight | 516.55 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inducer |
| Solubility | Solubleto2mMinethanolandto20mMinDMSO. |
| Source | Synthetic |
| Appearance | Orangetobrownsolid. |
| SMILES | C1=CC=CC=C1/C=C/C(C2=C(C(=C(C3=C2OC(C)(C)C=C3)O)CC4=C(C(=C(C(=C4O)C(C)=O)O)C)O)O)=O |
| InChI | InChI=1S/C30H28O8/c1-15-24(33)19(27(36)22(16(2)31)25(15)34)14-20-26(35)18-12-13-30(3,4)38-29(18)23(28(20)37)21(32)11-10-17-8-6-5-7-9-17/h5-13,33-37H,14H2,1-4H3/b11-10+ |
| InChIKey | DEZFNHCVIZBHBI-ZHACJKMWSA-N |
| SafetyPhrases | Classification:NotWHMIScontrolled.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection. |
| CiteThisProduct | Rottlerin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-394) |
BIOLOGicalDescription
| AlternativeNames | 3"-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2",4",6"-trihydroxy-5"-methylacetophenone |
| ResearchAreas | Cancer,Autophagy |
| PubChemID | 5281847 |
| ScientificBackground | RottlerinhasbeenshowntoinhibitproteinkinaseCaswellasCAMkinaseIII.ItisalsoapotentactivatorofmanyK+channelswhichareCa2+-activated.StudieshaveillustratedRottlerintoactasamitochondrialuncouplerwhichdepolarizesmembranepotential.Lastly,RottlerincaninduceautophagybyinhibitionofmTORC1signalling. |
| References | 1.GschwendtM.etal.(1994)BiochemBiophysResCommun.199(1):93-8. 2.WuS.,etal.(2007)JCellPhysiol.210(3):655-66. 3.SoltoffS.(2001)JBiolChem.276(41):37986-92. 4.BalgiA.,etal.(2009)PLoSOne.4(9):e7124. |
ProductImages
ChemicalstructureofRottlerin(SIH-394),aAutophagyinducer.CAS#:82-08-6.MolecularFormula:C30H28O8.MolecularWeight:516.55g/mol.
ProductCitations(0)
Currentlytherearenocitationsforthisproduct.
品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
