STRESS MARQ/马来酸罗格列酮/SIH-379-10MG/10MG
商品编号：
SIH-379-10MG
市场价：
¥1000.00
美元价：
600.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | RosiglitazoneMaleate |
| Description | Insulinsensitizer |
| Purity | >98% |
| CASNo. | 155141-29-0 |
| MolecularFormula | C18H19N3O3S•C4H4O4 |
| MolecularWeight | 473.5 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | AgoNIST |
| Solubility | SolubleinDMSO(3mg/ml)orDMF(10mg/ml) |
| Source | Synthetic |
| Appearance | Whitetooff-whitesolid |
| SMILES | C2=C(CC1SC(=O)NC1=O)C=CC(=C2)OCCN(C3=CC=CC=N3)C.O=C(O)C=C/C(=O)O |
| InChI | InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23) |
| InChIKey | YASAKCUCGLMORW-UHFFFAOYSA-N |
| SafetyPhrases | Classification:Caution:Substancenotyetfullytested.SafetyPhrases:S22-Donotbreathedust.S24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection |
| CiteThisProduct | RosiglitazoneMaleate(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-379) |
BIOLOGicalDescription
| AlternativeNames | 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| ResearchAreas | CellSignaling |
| PubChemID | 77999 |
| ScientificBackground | RosiglitazoneisapotentagonistforPPARγwithanEC50of43nMforthehumanreceptor.Itisanti-diabetic,workingasaninsulinsensitizerbybindingtothePPARγreceptorsinfatcellsandmakingthecellsmoreresponsivetoinsulin. |
| References | 1.WernerA.L.,&TravagliniM.T.(2001)Pharmacotherapy.21(9):1082-99. 2.McMorranM.,andVuD.(2001)CMAJ.165(1):82-3,86-7. 3.MalinowskiJ.M.&BolestaS.(2000)Clin.Ther.22(10):1151-68. 4.Cheng-LaiA.,&LevineA.(2000)HeartDis.2(4):326-33. 5.KnockG.A.,etal.(1999)Eur.J.Pharmacol.368(1):103-9. 6.BalfourJ.A.,&PloskerG.L.(1999)Drugs.57(6):921-30. 7.ParksD.J.,etal.(1998)Bioorg.Med.Chem.Lett.8(24):3657-8. |
ProductImages
ChemicalstructureofRosiglitazoneMaleate(SIH-379),aInsulinsensitizingagent.CAS#:122320-73-4.MolecularFormula:C18H19N3O3S.MolecularWeight:357.4g/mol.
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
