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当前位置: 首页 > 产品中心 > acid_base_buffer_solution > StressMarq/Roscovitine/SIH-472-2MG/2-mg
商品详细StressMarq/Roscovitine/SIH-472-2MG/2-mg
StressMarq/Roscovitine/SIH-472-2MG/2-mg
StressMarq/Roscovitine/SIH-472-2MG/2-mg
商品编号: SIH-472-2MG
市场价: ¥1040.00
美元价: 624.00
产地: 美国(厂家直采)
公司:
产品分类: 酸碱缓冲液
公司分类: acid_base_buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Overview:

ProductNameRoscovitine
Description

p34/cdc2inhibitor

Purity>95%(HPLC,TLC)
CASNo.186692-46-6
MolecularFormulaC19H26N6O
MolecularWeight354.4

Properties

StorageTemperature-20ºC
ShippingTemperatureShippedAmbient
ProductTypeInhibitor
SolubilitySolubleinDMSO
SourceSynthetic
AppearanceWhitetooff-whitesolid
SMILES[[email protected]](NC2=NC1=C(N=C[N]1C(C)C)C(=N2)NCC3=CC=CC=C3)(CO)CC
InChIInChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
InChIKeyBTIHMVBBUGXLCJ-OAHLLOKOSA-N
SafetyPhrasesClassification:Notahazardoussubstanceormixture.SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.
CiteThisProductRoscovitine(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-472)

BIOLOGicalDescription

AlternativeNames2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol,6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine,2(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
ResearchAreasCellSignaling
PubChemID160355
ScientificBackgroundRoscovitineisapotentandselectiveinhibitorofcyclin-dependentkinases(CDKs).ItisspecificallyselectiveforCDK1/cyclinBkinase,CDK2andCDK5/p35.ItinhibitsMphasepromotingfactorkinaseactivityandaffectscalciumchannelgating.
References1.DeAzevedo,etal.(1997)Eur.J.Biochem.243(1-2):518–526.

ProductImages

<p>Chemical structure of Roscovitine (SIH-472), a p34/cdc2 inhibitor. CAS #: 186692-46-6. Molecular Formula: C19H26N6O. Molecular Weight: 354.4 g/mol.</p>

ChemicalstructureofRoscovitine(SIH-472),ap34/cdc2inhibitor.CAS#:186692-46-6.MolecularFormula:C19H26N6O.MolecularWeight:354.4g/mol.

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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究,同时在其他领域也取得了一定成就,包括翻译后修饰,提供甲基化与乙酰基化抗体。其中,细胞应激领域主要包括热休克蛋白(HSP)领域。我们公司不仅在热休克蛋白领域领先全球,而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列,分别涉及抗体、蛋白、酶联免疫吸附试验(ELISA)试剂盒及小分子领域。