StressMarq/Rapamycin/SIH-212-5MG/5-mg
商品编号：
SIH-212-5MG
市场价：
¥2460.00
美元价：
1476.00
产品分类：
酸碱缓冲液
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Overview:
| ProductName | Rapamycin |
| Description | mTORinhibitor |
| Purity | >98% |
| CASNo. | 53123-88-9 |
| MolecularFormula | C51H79NO13 |
| MolecularWeight | 914.18 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | Solubleto100mMinethanol,andto50mMinDMSO |
| Source | Synthetic |
| Appearance | WhiteSolid |
| SMILES | C[[email protected]@H]1CC[[email protected]]2C[[email protected]@H](/C(=C/C=C/C=C/[[email protected]](C[[email protected]](C(=O)[[email protected]@H]([[email protected]@H](/C(=C/[[email protected]](C(=O)C[[email protected]](OC(=O)[[email protected]@H]3CCCCN3C(=O)C(=O)[[email protected]@]1(O2)O)[[email protected]](C)C[[email protected]@H]4CC[[email protected]]([[email protected]@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC |
| InChI | InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63- |
| InChIKey | QFJCIRLUMZQUOT-HPLJOQBZSA-N |
| SafetyPhrases | Classification:Harmful.Maybeharmfulifinhaled,swallowedorabsorbedthroughskin.SafetyPhrases:S22-DonotbreathedustS24/25-AvoidcontactwithskinandeyesS36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotectionRiskPhrases:R68-PossIBLeriskofirreversibleeffect |
| CiteThisProduct | Rapamycin(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-212) |
BIOLOGicalDescription
| AlternativeNames | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-2-propanyl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene2,3,10,14,20-pentone |
| ResearchAreas | Cancer,Apoptosis,CancerGrowthInhibitors,mTORInhibitors |
| PubChemID | 5284616 |
| ScientificBackground | RapamycinorSirolimusisanimmunosuppressantandantifungal.Itinhibitstheresponsetointerleukin-2,andthereforeblocksactivationofTandBcells.ItbindsFKBP12whichtheninhibitsthemTORpathway(1).ThereisalsopotentialtreatmentforAlzheimer;s,autismandHIVinfection(2-3). |
| References | 1.GruppusoP.A.,BoylanJ.M.,andSandersJ.A.(2011)CellCycle.10(7):EPub. 2.EhningerD.,etal.(2008)Nat.Med.14(8):843-848. 3.DoniaM.,McCubreyJ.A.,BendtzenK.,andNicolettiF.(2010)BrJClinPharmacol.70(6):784-793. |
ProductImages
ChemicalstructureofRapamycin(SIH-212),amTORinhibitor.CAS#:53123-88-9.MolecularFormula:C51H79NO13.MolecularWeight:914.18g/mol.
ProductCitations(0)
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品牌介绍
StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。
