StressMarq/Anti-RAGE Antibody/SPC-1292D-P594/100-µl-免疫在线蚂蚁淘旗下平台

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商品详细StressMarq/Anti-RAGE Antibody/SPC-1292D-P594/100-µl

StressMarq/Anti-RAGE Antibody/SPC-1292D-P594/100-µl

商品编号： SPC-1292D-P594

品牌： StressMarq Biosciences

市场价： ¥6180.00

美元价： 3708.00

产地：美国(厂家直采)

公司：

产品分类：酸碱缓冲液

公司分类： acid_base_buffer_solution

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Overview:

ProductName RAGEAntibody

Description

RabbitAnti-HumanRAGEPolyclonal

SpeciesReactivity Human

Applications WB,IHC,ICC/IF

AntibodyDilution WB(1:1000),IHC(1:200);optimaldilutionsforassaysshouldbedeterminedbytheuser.

HostSpecies Rabbit

ImmunogenSpecies Human

Immunogen AsynthesizedpeptidederivedfromhumanRAGE

Conjugates

AlkalinePhosphatase,APC,ATTO390,ATTO488,ATTO565,ATTO594,ATTO633,ATTO655,ATTO680,ATTO700,Biotin,FITC,HRP,PE/ATTO594,PerCP,RPE,Streptavidin,Unconjugated

Properties

StorageBuffer	PBSpH7.4,50%glycerol,150mMNaCl,0.02%sodiumazide
StorageTemperature	-20ºC
ShippingTemperature	BlueIceor4ºC
Purification	AffinityPurified
Clonality	Polyclonal
Isotype	IgG
Specificity	Detects~42kDa,endogenouslevelsoftotalRAGE.
CiteThisProduct	StressMarqBiosciencesCat#SPC-1292,RRID:AB_2713061
CertificateofAnalysis	A1:1000dilutionofSPC-1292wassufficientfordetectionofRAGEin10µgofhumanbraincelllysatesbyECLimmunoblotanalysisusingGoatAnti-RabbitIgG:HRPasthesecondaryantibody.

BIOLOGicalDescription

AlternativeNames	Advancedglycosylationendproduct-specificreceptorAntibody,AgerAntibody,MGC2235Antibody,RAGE_HUMANAntibody,ReceptorforadvancedglycosylationendproductsAntibody
ResearchAreas	Alzheimer"sDisease,AlzheimersDisease,Atherosclerosis,CardiovascularSystem,Neurodegeneration,Neuroscience
CellularLocalization	Cellmembrane,Secreted
AccessionNumber	NP_001127.1
GeneID	177
SwissProt	Q15109
ScientificBackground	RAGE,thereceptorforadvancedglycationendproducts,isa35kDatransmembranereceptoroftheimmunoglobulinsuperfamilywhichwasfirstcharacterizedin1992byNeeperetal.Itisalsocalled"AGER".TheincreasedexpressionofRAGEisassociatedwithmanydisorders,suchasdiabeticvasculopathy,neuropathy,retinopathyandneuropathy,Alzheimer’sdiseaseandimmune/inflammatoryreactionsofthevesselwalls.ItisreportedthatRAGEalongwithAmphoterinstimulatesmyoblastdifferentiationbythecombinedeffectofstimulationofdifferentiationandinhibitionofproliferation,andderegulationofRAGEexpressioninmyoblastsmightcontributetotheirneoplastictransformation.
References	1.NeeperM.etal.(1992)TheJournalofBiologicalChemistry267(21):14998–5004. 2.BierhausA.etal.(2001)Diabetes50(12):2792–808. 3.HudsonBI.etal.(2001)Diabetes50(6):1505–11.

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PE/ATTO594

PE/ATTO594isatandemconjugate,wherePEisexcitedat535nmandtransfersenergytoATTO594viaFRET(fluorescenceresonanceenergytransfer),whichemitsat627nm.

Overview:

Highfluorescenceyield
HighphotostABIlity
Veryhydrophilic
Excellentsolubilityinwater
Verylittleaggregation

PE/ATTO594Datasheet

PE-ATTO 594 Fluorophore Conjugate Excitation and Emission Spectra

OpticalProperties:

λ_ex =535nm

λ_em =627 nm

Laser = 488to561nm

品牌介绍

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。

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